Comparison of the Efficacy of 3 modalities for the treatment of Striae Distensae or Stretchmarks - Fractional Carbon Dioxide Laser versus Autologous Platelet Rich Plasma versus Microneedling with topical Aloe Vera Gel.
Not Applicable
- Conditions
- Health Condition 1: R234- Changes in skin texture
- Registration Number
- CTRI/2023/06/054031
- Lead Sponsor
- Dr Sumedha Tirthani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients of both genders with striae Distensae of all grades over any site on the body
2. Patients who have not taken treatment for striae distensae either topppical or systemic in the past 6 months
Exclusion Criteria
1.Patients on systemic isotretinoin or corticosteroids.
2.Patients with history of keloid formation.
3.Patients with any connective tissue disease.
4.Patients with disease affecting the wound-healing process.
5.Patients with other systemic illness – cardiac, renal, hepatic illness.
6.Severely Immunocompromised
7.Pregnancy, Lactation
8.Patients who have cold intolerance
9.Patients taking photosensitive drugs and photosensitivity
10.Patient not willing for study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Measurement of efficacy of modalities on the basis of quartile grading score. <br/ ><br>2. % reduction in width of Striae <br/ ><br>3. Patient satisfaction using Likert Satisfaction scaleTimepoint: 1. before each setting - every 3 weeks <br/ ><br>2, 3 - at end of 6 settings and 3 weeks after the last setting - at 15 weeks
- Secondary Outcome Measures
Name Time Method Post procedural adverse effects & healing effects of Fractional Carbon Dioxide Laser, PRP, and Microneedling with topical aloe vera gel in treatment of striae distensae.Timepoint: 1. before each setting - every 3 weeks, at end of 6 settings