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Clinical Trials/IRCT2013042812294N3
IRCT2013042812294N3
Completed
Phase 2

Partial Lateral Internal Sphincterotomy Versus Combined Botulinum Toxin A Injection and Topical Application of Diltiazem in treatment of chronic anal fissure

Vice chancellor for research, Tehran University of Medical Sciences0 sites99 target enrollmentStarted: TBDLast updated:

Overview

Phase
Phase 2
Status
Completed
Sponsor
Vice chancellor for research, Tehran University of Medical Sciences
Enrollment
99

Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
18 years to 100 years (—)
Sex
All

Inclusion Criteria

  • diagnosis of chronic anal fissure on physical examination (based on having indurations at the edges and having at least two criteria of these three including skin tag; hypertrophied anal papillae and exposed internal sphincter muscle fiber) by an experienced
  • colorectal surgeon associated with painful defecation for at least 2 month; age between 18 and 100 years old.
  • Exclusion criteria:
  • acute anal fissure (experiencing symptoms less than two months); pregnancy; secondary anal fissure; hypersensitivity to DTZ or BTA; cardiovascular disease; previous history of anal surgery; atypical fissure and chronic headache.

Exclusion Criteria

  • Not provided

Investigators

Sponsor
Vice chancellor for research, Tehran University of Medical Sciences

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