Investigating the effects of zinc sulfate and vitamin C supplementation in sepsis management in septic patients

Phase 3

• Conditions: Sepsis, unspecified organism.; Sepsis, unspecified organism; A41.9

• Registration Number: IRCT20080901001165N67
• Lead Sponsor: Bagheiat-allah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 8 March 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Having suspected or proven infection;
Increasing 2 points or more of SOFA score compared to the baseline;
The patient or his/her guardian has informed and free written consent to participate in the study;

Exclusion Criteria

Multi organ dysfunction;
Glasgow Coma Score (GCS) less than 4;
The patient needs emergency dialysis due to severe acidosis or end stage renal disease;
Pregnancy;
Breastfeeding;
Being NPO for any reasons;
Having kidney stones as his/her medical history;
Having hypersensitivity reactions with the intervention in the past;

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
30-days Mortality rate;. Timepoint: Daily, till 30 days. Method of measurement: Vital signs assessment.

Secondary Outcome Measures

Name	Time	Method
ength of ICU stay. Timepoint: Daily, until the discharge or death. Method of measurement: Medical record assessment.;Length of hospital stay. Timepoint: Daily, until the discharge or death. Method of measurement: Medical record assessment.;Vasopressor dose. Timepoint: Day 1, 5 and 10. Method of measurement: Check the medication list.;SOFA score changes. Timepoint: Day 1, 5 and 10. Method of measurement: Sequential Organ Failure Assessment(SOFA) score.