EUCTR2021-003676-13-AT
Active, not recruiting
Phase 1
A prospective randomized, double blind, controlled, safety and non-inferiority study of esketamine plus propofol compared to methohexital anesthesia for electroconvulsive therapy - Comparison of ketofol and methohexital anesthesia for ECT
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- severe uni- or bipolar depression (F32.2, F32.2, F33.2, F33.3, F31.4, F31.5)
- Sponsor
- Medical University of Vienna
- Enrollment
- 100
- Status
- Active, not recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\-male or female inpatients
- •\-age \= 18 years
- •\-ICD\-10 diagnosis of severe uni\- or bipolar depression (F32\.2, F32\.2, F33\.2, F33\.3, F31\.4, F31\.5\)
- •\-HAMD17 \= 24
- •ability to understand and willingness to sign written informed consent document
- •\-antidepressant and antipsychotic medication in steady state for at least 7 days prior inclusion
- •\-negative urine pregnancy test in women
- •\-anesthesiological approval for ECT (ASA \= 3\)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
Exclusion Criteria
- •\-severe somatic or neurological disease (esp. current or previous history of intracranial hypertension, uncontrolled severe hypertension, bleeds or aneurysm, recent myocardial infarction)
- •\-current or past history of schizophrenia or schizoaffective disorder
- •\-clinical relevant abnormalities on a general physical examination and routine laboratory screening
- •\-pregnancy, breast feeding
- •\-known allergy to the study drugs or compounds of the latter
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
A prospective randomised, double-blind controlled trial of intravenous aminophylline versus placebo in patients with acute exacerbations of COPDISRCTN17312089Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)80
Recruiting
Phase 1
A prospective, double-blind, randomized controlled clinical study of Shenshuai II granule in delaying the progression of chronic glomerulonephritis (CKD3 stage)ITMCTR2000003740Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Not yet recruiting
Phase 1
A prospective, double-blind, randomized controlled trial of TCM syndrome differentiation combined with andis classification in the treatment of stage IV diabetic kidney disease of spleen kidney qi deficiency typeITMCTR2000003821onghua Hospital Shanghai University of Traditional Chinese Medicine
Not yet recruiting
Phase 4
Is Diosmin (Venusmin) effective in treating haemorrhoidsHealth Condition 1: K649- Unspecified hemorrhoidsCTRI/2020/11/028921Walter Bushnell Laboratories Pvt Ltd
Not yet recruiting
Not Applicable
To compare the effect of Coadministration of two different doses of injection of blood pressure raising medicines (phenylephrine) with uterine contractor (oxytocin) on the prevention of uterine contractor induced Reduction in blood pressure in caesarean delivery.Health Condition 1: O82- Encounter for cesarean delivery without indicationHealth Condition 2: O82- Encounter for cesarean delivery without indicationCTRI/2022/04/042110Department of Anaesthesiology SMS Medical College