Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy

Completed

• Conditions: Dysthyroid Orbitopathy

• Registration Number: NCT00665795
• Lead Sponsor: University of Sao Paulo

Brief Summary

The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging.

Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.

Detailed Description

Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging:

Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).

Study Timeline

• Study Start: 2005-07
• Study First Submitted: 2008-04-22
• Study First Submitted QC: 2008-04-22
• Study First Posted: 2008-04-24
• Status Verified: 2013-11
• Primary Completion: 2013-11
• Study Completion: 2013-11
• Last Update Submitted: 2013-11-17
• Last Update Posted: 2013-11-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Graves´Orbitopathy diagnosed based on previously reported criteria
• Age above 20 years
• Good cooperation for performing Visual Field test
• Spherical refraction within ± 5 D and cylinder correction within ± 3 D

Exclusion Criteria

• Graves´Orbitopathy not diagnosed

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
screening indexes for dysthyroid optic neuropathy	indexes above 60% of orbital apex crowding were high suspected for DON

Trial Locations

Locations (1)

General Hospital - University of Sao Paulo - School of Medicine; 🇧🇷 São Paulo, Brazil