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Clinical Trials/NCT02576392
NCT02576392
Completed
Not Applicable

Reducing the Use of Opioid Therapy Following Orthopedic Surgery: A Randomized Controlled Trial

Kaiser Permanente0 sites561 target enrollmentJuly 1, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post-operative Pain
Sponsor
Kaiser Permanente
Enrollment
561
Primary Endpoint
Average morphine equivalents
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

This randomized trial evaluates an intervention to minimize use of opioids following total hip and total knee replacement. Half the participants will receive an intervention (mailed educational materials, followed by a pharmacist call), and half will receive usual care.

Detailed Description

Surgeons and anesthesiologists prescribe opioids and other analgesic medications for acute, post-surgical pain. Recent studies have reported that some patients persist in taking opioids for months beyond the surgery. While opioids are commonly used for pain management following surgery, patients and their providers often don't have a planned method to optimize opioid exposure. This can lead to patients entering a cycle of opioid use that is difficult to manage, because, as opioid exposure is continued, pain relief is reduced and side effects increase. The investigators' study is aimed at reducing opioid exposure following total hip and total knee replacement.

Registry
clinicaltrials.gov
Start Date
July 1, 2015
End Date
March 31, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • total hip replacement or total knee replacement
  • 1 year membership with KPNW prior to enrollment

Exclusion Criteria

  • managed by pain clinic, in other pain management trial
  • patients at low risk of persistent opioid use

Outcomes

Primary Outcomes

Average morphine equivalents

Time Frame: 90 days

post surgery use of opioids

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