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临床试验/CTRI/2024/06/068233
CTRI/2024/06/068233尚未招募不适用

Correlation between high sensitive cardiac troponin T levels and myocardial injury in children with acyanotic congenital heart diseases between 1 to 5 years of age - a one year case control study at a tertiary care centre

Jawaharlal Nehru medical college1 个研究点 分布在 1 个国家目标入组 84 人开始时间: 2024年6月13日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
84
试验地点
1
主要终点
to find out if children with acyanotic congenital heart diseases have raised high sensitive cardiac troponin T levels which correlates to myocardial injury

研究概览

简要总结

Most congenital heart diseases do not have any identifiable etiology and there is no effective strategy for their prevention. Vast majority of acyanotic congenital heart diseases are diagnosed early in high-income households. Low and middle income households are where most births happen and a lack of awareness and delay in diagnosis is a significant risk to the survival of the children. Furthermore there is no established reference value of high sensitive cardiac troponin T values in paediatric age group which limits the use of this investigation hence delaying diagnosis and treatment. By estimating the levels of high sensitive cardiac troponin T and correlating it with myocardial injury, apositive correlation can ensure early surgical intervention of acyanotic congenital heart diseases before irreversible damage occurs.

研究设计

研究类型
Observational

入排标准

年龄范围
1.00 Year(s) 至 5.00 Year(s)(—)
性别
All

入选标准

  • children between 1 to 5 years of age who are a known case of acyanotic congeniytal heart disease will be taken as cases.
  • the controls will be healthy children without acyanotic congenital heart diseases.

排除标准

  • children between 1 to 5 years of age who are in septic shock, active NEC, infective endocarditis, renal failure, lung failure, on cardiotoxic drugs, intracranial haemorrhage, heart failure due to any cardiomyopathies, pericarditis or coronary artery diseases.

结局指标

主要结局

to find out if children with acyanotic congenital heart diseases have raised high sensitive cardiac troponin T levels which correlates to myocardial injury

时间窗: to find out if children with acyanotic congenital heart diseases have raised high sensitive cardiac troponin T levels which correlates to myocardial injury will be found out at baseline after investigation results come

次要结局

  • to compare the levels of high sensitive cardiac troponin T in children with different types of acyanotic congenital heart diseases(1 year)

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Papani Sruthika

Jawarhal nehru medical college

研究点 (1)

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