A prospective observational study to evaluate the prescribing pattern and microbial sensitivity of antimicrobial agents in Gram-negative severe sepsis/septic shock patients in medical intensive care unit at tertiary care hospital.

Recruiting

Brief Summary: | | |

| --- | --- |

| Protocol Title

  A prospective observational study to evaluate the prescribing pattern and microbial sensitivity of antimicrobial agents in Gram-negative severe sepsis/septic shock patients in medical intensive care unit at tertiary care hospital.

| Protocol No:

PPMS-01

| Version number

1.0, Dated-5/09/13

| Primary objective

    Secondary objective

   To evaluate the prescribing pattern and microbial sensitivity of antimicrobial agents in Gram- negative severe sepsis/ septic shock patients in MICU at tertiary care hospital.

1. To determine the epidemiology of Gram- negative severe sepsis/septic shock in MICU at tertiary care hospital.

2. To determine the clinical outcomes of Gram- negative severe sepsis/septic shock patients admitted in the MICU.



| Study design

  Prospective Observational study

| Study Duration

6 months

| Methodology

In this study, data of the patients, who suffered from Gram-negative severe sepsis/septic shock, will be collected prospectively, from MICU, Max Super Specialty Hospital, Patpargunj, New Delhi, and the prescribing pattern and microbial sensitivity will be studied and evaluated

| Study Population

  Both males and females

| Data Collection

All the variables will be noted in the data collection sheet.

| Ethics and Responsibility

  The protocol will be submitted to IEC of Max Super Specialty Hospital.

Recruitment & Eligibility

Inclusion Criteria

â€¢Patients with severe sepsis/septic shock admitted to the medical intensive care unit.
â€¢Patients aged above 18 years and below 65 years â€¢Patients who are receiving antimicrobial agents.

Exclusion Criteria

â€¢Patients with less than 8 hours of length of stay in the ICU.

Primary Outcome Measures

Name	Time	Method
To determine the major antibiotic prescribed in Gram- negative severe sepsis/ septic shock patients admitted in MICU.	After recruitment we analyze our outcome.
2. To determine the Gram- negative micro-organism isolated in the positive culture and their sensitivity against the antimicrobial agents.	After recruitment we analyze our outcome.

Secondary Outcome Measures

Name	Time	Method
Not Applicable	Not Applicable

Locations (1): Max Super Speciality Hospital
🇮🇳
Delhi, DELHI, India
Max Super Speciality Hospital
🇮🇳Delhi, DELHI, India
DrYP Singh
Principal investigator
08800531155
yogendra.singh2@maxhealthcare.com