Exosome therapy in recurrent implantation failure

Phase 1

• Conditions: Recurrent implantation failure.

• Registration Number: IRCT20210228050535N2
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 44

Inclusion Criteria

Women with recurrent implantation failure who did not conceive after at least three embryo transfer cycles or after transferring at least ten good-quality embryos.
Age between 20–40 years
With Body Mass Index (BMI) under 30 kg/m2

Exclusion Criteria

Uterine abnormalities in hysteroscopy and hysterosalpingography
Hematologic disorders
Hormonal disorders
Immunologic disorders
Chromosomal abnormalities and genetic disorders in parents

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Chemical pregnancy rate. Timepoint: Two weeks after embryo transfer. Method of measurement: Measurement of B-HCG.;Clinical pregnancy rate. Timepoint: Five weeks after embryo transfer. Method of measurement: Sonography.;Abortion rate. Timepoint: During pregnancy. Method of measurement: Sonography.

Secondary Outcome Measures

Name	Time	Method
ive birth rate. Timepoint: End of pregnancy. Method of measurement: Parturition.;Implantation rate. Timepoint: Six weeks after embryo transfer. Method of measurement: The number of gestational sacs divided by the number of transferred embryos.;Ongoing pregnancy. Timepoint: 20th week of pregnancy. Method of measurement: Sonography.