NCT01627522已完成2 期
Evaluation of Finastride Effect in Different Dosage on the Amount of Perioperative Bleeding in Transurthral Resection of Prostate
适应症
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Perioperative Hb Drop
研究概览
简要总结
Preoperative use of finastride will decrease the amount of perioperative blood loss during and after TURP
The effect of finastride on decreasing the amount of perioperative blood loss during and after TURP is dose dependent
Finastride will decrease microvascular density in prostate tissue and this effect is dose dependent
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patients with BPH that require TURP
排除标准
- •Previous prostate surgery
- •Prostate Cancer
- •Coagulopathy
- •The use of NSAIDs, Anticoagulants, Antiplatelet drugs
研究组 & 干预措施
Finastide low dose
Active Comparator
2 weeks of daily 5mg finastride before operation
干预措施: TURP (Procedure)
Finastide high dose
Active Comparator
4 weeks of daily 5mg finastride before operation
干预措施: TURP (Procedure)
Control
No Intervention
Control
结局指标
主要结局
Perioperative Hb Drop
时间窗: 24 hours after surgery
次要结局
未报告次要终点
研究者
Alireza Aminsharifi
Assistant professor of Urology
Shiraz University of Medical Sciences
研究点 (1)
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