Maternal Periodontal Status and Gingival Crevicular Fluid Levels of Interleukin-6, Interleukin-35, and Interleukin-37 in Preeclampsia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 主要终点
- maternal periodontal clinical parameters and IL-37 and IL-35 and IL-6 levels
研究概览
简要总结
Background: The purpose of this study is to examine the relationship between maternal preeclampsia and periodontal parameters and the correlation of these two disorders with maternal gingival crevicular fluid levels (GCF) of interleukin (IL)-35, interleukin-37 and interleukin-6. The investigators also investigated their relation to the severity of preeclampsia.
Methods: 82 preeclamptic women were recruited to the study (29 healthy pregnant women, 30 mild preeclamptic patient, 23 severe preeclamptic patient ). The clinical periodontal parameters and GCF samples were collected in the first day of puerperium.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Aged between 18 and 45 years
- •25 and 40 weeks of gestation.
- •Healthy pregnants, mild and severe preeclampsia
排除标准
- •Patients with accompanying diseases
- •multiple gestations
- •congenital abnormalities were excluded from the study.
结局指标
主要结局
maternal periodontal clinical parameters and IL-37 and IL-35 and IL-6 levels
时间窗: 6 months
IL-37 IL-35 and IL-6 levels in maternal gingival crevicular fluid levels between the three groups
次要结局
未报告次要终点
研究者
Hacer Sahin Aydinyurt
Principal investigator
Yuzuncu Yıl University