Differences in Ovarian Aging Between Caucasian and Indian Women
- Conditions
- Age of the Patients and the Body Mass Index in Both Groups
- Registration Number
- NCT02210013
- Lead Sponsor
- IVI Madrid
- Brief Summary
The investigators want to carry out a prospective study of 400 infertile Caucasian and Indian women who will undergo a controlled ovarian stimulation for in vitro fertilization (IVF). The investigators will collect data about ovarian reserve markers and also the results after ovarian stimulation in both ethnic groups.The aim is to identify differences in ovarian response after IVF stimulation between both groups.
- Detailed Description
A total of 200 Caucasian patients and 200 Indian patients who will attend the first or second IVF cycle will be included.
The date we will collect in both groups include the age, the body mass index, and the ovarian reserve markers like the antral follicle count (AFC), the follicle stimulation hormone (FSH) and antimullerian hormone (AMH) serum levels.
The investigators will also determine the number of oocytes retrieved and the metaphase two oocytes in both groups after IVF stimulation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 400
- Women aged < 42 years old, with both ovaries present, undergoing a first or second IVF treatment due to male factor, tubal disease or previous failed intrauterine insemination (IUI).
- Women diagnosed of polycystic ovary syndrome according to Rotterdam criteria, endometriosis stage III-IV, or previous pelvic inflammatory disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AMH levels produced by granulosa cells day 1 AMH levels (ng/mL) as well as AFC in both ethnic groups.
- Secondary Outcome Measures
Name Time Method Number of oocytes day 1 The number of oocytes retrieved as well as the mature oocytes after IVF ovarian stimulation