Factors Associated With Dermatoporosis

Completed

• Conditions: Senile Purpura
• Interventions: Other: Questionnaire about associated factors; Diagnostic Test: Self questionnaire diagnostic tool; Other: Physical Examination

• Registration Number: NCT05037604
• Lead Sponsor: Universidad Autonoma de San Luis Potosí

Brief Summary

Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years.

The objective was to determine factors associated with this diagnosis in \>60 years old patients of the outpatient clinic in the Hospital Central "Dr. Ignacio Morones Prieto " San Luis Potosí, México.

An observational, cross-sectional, descriptive, and analytical study was performed. Patients \>60 years old were selected. A clinical history, clinical examination, and application of a validated diagnostic self-questionnaire were performed.

Detailed Description

Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years.The objective was to determine factors associated with this diagnosis in \>60 years old patients of the outpatient clinic in the Hospital Central "Dr. Ignacio Morones Prieto " San Luis Potosí, México.

An observational, cross-sectional, descriptive and analytical study was performed. Through consecutive non-probabilistic sampling, patients \> 60 years old were selected, who underwent a clinical history, clinical examination, and the application of a validated diagnostic self-questionnaire. To determine the association of the factors, a multivariate logistic regression analysis, it will be used the PRIMERv6 software with the PERMANOVA package. A p \<0.05 was considered significant. The normality of the distribution of the continuous variables was evaluated with the Shapiro Wilk test. The Student's t test was performed on variables that met the homogeneity of variance requirements. In the variables that did not meet this criterion, a non-parametric analysis was performed with the Mann U Whitney test. For the analysis of categorical variables, Fisher's exact test or chi-square test was used. Continuous variables were reported by mean (median) \[Q1, Q3\] (min - max) and by standard deviations as their distribution corresponds. Nominal categorical variables were expressed as frequencies

Study Timeline

• Study Start: 2018-08-01
• Primary Completion: 2018-11-30
• Study Completion: 2019-04-30
• Status Verified: 2021-08
• Study First Submitted: 2021-08-23
• Study First Submitted QC: 2021-08-30
• Last Update Submitted: 2021-08-30
• Study First Posted: 2021-09-08
• Last Update Posted: 2021-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 315

Inclusion Criteria

• Patients over 60 years

Exclusion Criteria

• Patients in whom physical examination cannot be performed due to the use of orthopedic devices such as splints, bandages, etc.
• Patients with whom interviewer-patient verbal communication is difficult due to some hearing or neurological deficit.
• Patients with neurological, psychiatric disorders who are unable to provide reliable information. (disorganized, incoherent speech, cognitive deficit)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control	Physical Examination	Patients not diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed.
Cases	Questionnaire about associated factors	Patients diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed.
Cases	Physical Examination	Patients diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed.
Control	Questionnaire about associated factors	Patients not diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed.
Control	Self questionnaire diagnostic tool	Patients not diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed.
Cases	Self questionnaire diagnostic tool	Patients diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed.

Primary Outcome Measures

Name	Time	Method
Factors associated with Dermatoporosis	At time of enrollment	Presence of factors related to age, sex, personal history of diseases, chronic oral treatments, gyneco-obstetrics background, chronic photoexposure
Diagnostic by self assesment tool	At time of enrollment	Diagnostic of dermatoporosis made by self assesment tool
Physical examination	At time of enrollment	Presence of pseudoscars (stellate scars) in the physical examination

Trial Locations

Locations (1)

Hospital Central "Dr. Ignacio Morones Prieto"; 🇲🇽 San Luis Potosi, Mexico