IRCT20200408046990N13招募中3 期
Evaluation of oral nano-silymarin formulation efficacy in prevention of hepatotoxicity induced by doxorubicin-cyclophosphamide chemotherapy regimen in patients with non-metastatic breast cancer
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- Female
入选标准
- •Age between 18-65 y
- •Patients with diagnosis of non-metastatic breast cancer who will be treated by doxurobicin after mastectomy
- •Signing the written consent
排除标准
- •Viral hepatitis
- •History of hypersensitivity to silymarin or similar compounds
- •Pregnancy and lactation
- •Any kind of liver injury resulting in rise of liver enzymes or bilirubin to higher than upper limit normal
- •Renal failure
- •Concomitant use of heptotoxic agents or antioxidants
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