A randomised controlled trial of the efficacy of a carrageenan nasal spray when taken during a cold in reducing asthma exacerbations as measured by the asthma control questionnaire.
Phase 3
Completed
- Conditions
- Asthma exacerbation during a coldColdsRespiratory - AsthmaInfection - Studies of infection and infectious agents
- Registration Number
- ACTRN12615001166561
- Lead Sponsor
- Julian Crane
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 361
Inclusion Criteria
People who have ever been doctor diagnosed with asthma, and who have had at least one cold in the past 12 months with asthma symptoms.
Exclusion Criteria
Those with COPD (doctor diagnosed), those who plan to use a nasal spray for another condition during the study period, those whose asthma does not worsen with a cold, those who have a previous sensitivity or allergy to carrageenan or other seaweed products, a history of nasal polyps, or those with 'current unstable asthma' which we define as having been hospitalised for asthma within the last 2 months or use of oral corticosteroids in the past month.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure will be the difference from baseline in ACQ scores with a cold between the placebo and active groups. [After 7 days of having a cold (ACQ score in past 7 days). ]
- Secondary Outcome Measures
Name Time Method