The Effect of Salba (Salvia Hispanica L) Versus Flax on Postprandial Blood Glucose Response and Subjective Appetite in Healthy Individuals
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Unity Health Toronto
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Change in Postprandial Blood Glucose
Study Overview
Brief Summary
The purpose of this study is to determine whether drinks containing Salvia hispanica L (Salba) or Flax lower postprandial blood glucose levels and improve appetite in healthy individuals.
Detailed Description
Dietary fibre has been implicated in improving many risk factors associated with Type 2 Diabetes and Cardiovascular Disease (CVD). However, on average, Norther Americans consume less than half of the recommended amount set by health agencies. It has been proposed that the health benefits of dietary fibre may be attritbuted to rheological characteristics such as viscosity. Salvia hispanica L (Salba) and Flax are nutritionally similar. The primary objective of this research trial is to study the effects of Salba and Flax on postprandial glycemia and appetite in healthy individuals.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Prevention
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •BMI less than 35 kg/m^2
Exclusion Criteria
- •known history of liver or kidney disease, diabetes, hypertension, stroke, or myocardial infarctions, thyroid disease, gastrointestinal disease, or AIDS
- •subjects using medications or Natural Health Products
Arms & Interventions
Salba
50g glucose 25g ground Salba (Salba Corporation Ltd, Buenos Aires, Argentina) 200ml water
Intervention: Salba (Dietary Supplement)
Flax
50g glucose 31g ground Flax (Bob's Red Mill Natural Raw Whole Flaxseed) 200ml water
Intervention: Flax (Dietary Supplement)
Control
50g glucose 200ml water
Intervention: Control (Dietary Supplement)
Outcomes
Primary Outcomes
Change in Postprandial Blood Glucose
Time Frame: 2 Hours
At each visit, postprandial blood glucose will be measured via capillary blood samples, at 15, 30, 45, 60, 90, and 120 minutes after intake of test meals
Secondary Outcomes
- Change in Subjective Satiety(2 Hours)
Investigators
Vladimir Vuksan
Research Scientist & Professor
Unity Health Toronto