Respiratory Variability for Respiratory Monitoring During the Postoperative Recovery Period
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Variation of the Tidal volume (Vt) between the preoperative and the postoperative period
研究概览
简要总结
The research consist of measuring respiratory variability of several variables of the respiratory pattern at rest and during exercise using a thoracic movement measuring technique. The objective is to confirm the ability of this technique to measure the respiratory variability in healthy subjects comparing to flow measurements by a pneumotachograph. In a second step, the thoracic movement technique is applied to measure respiratory variability before and after surgery in patients after abdominal surgery with laparotomy. The objective is to observe a decrease of variability in subjects developing or at risk to develop a postoperative pulmonary complication.
详细描述
The incidence of Postoperative Pulmonary Complications after non-thoracic surgery varie between 2 and 19%. Postoperative Pulmonary Complications are associated with an increase of morbi-mortality and longer hospital stays. However, few possibilities are available to identify Postoperative Pulmonary Complications except predictions scores and SpO2, which decreases only face to a significant lung disease. Besides, the respiratory variability decreases during pulmonary stress situations, and is associated with an increase of mortality during mechanical ventilation. The hypothesis is that a decrease of the respiratory variability between the preoperative and the postoperative measures is associated with an increase of Postoperative Pulmonary Complications . However there is no mesuring tool of easy access in clinical practice. That is why, in a first step, a thoracic sensor belt will be tested on healthy subjects. This sensor belt is available to measure the respiratory variability.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Physiological step :
- •adults without any acute or chronic disease with a significant impact on daily life, particularly no cardio-respiratory disease.
- •Smokers can be included.
- •Free and informed consent signed.
- •Clinical step :
- •adults undergoing abdominal surgery with laparotomy, in emergency or scheduled,
- •in Martinique and Guadeloupe.
- •Free and informed oral consent.
排除标准
- •Pregnant,breast feeding women,
- •intubated patients or with criteria of imminent intubation
- •subject unable to give his free and informed consent
结局指标
主要结局
Variation of the Tidal volume (Vt) between the preoperative and the postoperative period
时间窗: 7 days
Measure the respiratory variability in patients with abdominal surgery with laparotomy just before the anaesthetic induction and in the postoperative stage after extubation with a belt equipped with an external sensor.
次要结局
未报告次要终点