Oral Caffeine and Spinal-Induced Hypotension
Not Applicable
Recruiting
- Conditions
- Spinal HypotensionCaffeine
- Interventions
- Drug: Placebo
- Registration Number
- NCT07076654
- Lead Sponsor
- Cairo University
- Brief Summary
Hypotension after spinal anesthesia is critical. Thus several interventions have been proposed to mitigate such effect.
- Detailed Description
Hypotension is a critical issue related to spinal anesthesia during cesarean delivery. Researchers of this study aimed to evaluate the impact of preoperative oral caffeine on the incidence of spinal hypotension during cesarean delivery.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
- full term pregnant
- undergoing elective cesarean delivery
Exclusion Criteria
- patient refusal
- baseline systolic pressure < 100 mmHg
- contraindication to spinal anesthesia
- allergy to caffeine
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Caffeine Caffeine (200 mg) Patients will receive oral caffeine 200 mg before spinal anesthesia Control group Placebo Will receive placebo before spinal anesthesia
- Primary Outcome Measures
Name Time Method Incidence of spinal hypotension After spinal anesthesia till delivery Decrease systolic blood pressure \< 20% of baseline value
- Secondary Outcome Measures
Name Time Method Time to first hypotensive episode after induction of spinal anesthesia time to incidence of hypotension
Incidence of severe hypotension After onset of spinal anesthesia reduced systolic pressure \< 60% of baseline value
APGAR score at 5 minutes after delivery APGAR score calculation at 5 minutes
Umbilical artery pH At 5 minutes after delivery Umbilical artery blood gases
Trial Locations
- Locations (1)
Cairo University
🇪🇬Cairo, Cairo Governorate, Egypt
Cairo University🇪🇬Cairo, Cairo Governorate, Egyptcairo universityContact01275716942kasralainirec@gmail.com