NCT07076654已完成不适用
Effectiveness of Preoperative Oral Caffeine in Preventing Spinal-Induced Hypotension During Cesarean Delivery: A Double Blind Randomized Controlled Trial
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Incidence of spinal hypotension
研究概览
简要总结
Hypotension after spinal anesthesia is critical. Thus several interventions have been proposed to mitigate such effect.
详细描述
Hypotension is a critical issue related to spinal anesthesia during cesarean delivery. Researchers of this study aimed to evaluate the impact of preoperative oral caffeine on the incidence of spinal hypotension during cesarean delivery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •full term pregnant
- •undergoing elective cesarean delivery
排除标准
- •patient refusal
- •baseline systolic pressure < 100 mmHg
- •contraindication to spinal anesthesia
- •allergy to caffeine
研究组 & 干预措施
Caffeine
Active Comparator
Patients will receive oral caffeine 200 mg before spinal anesthesia
干预措施: Caffeine (200 mg) (Drug)
Control group
Placebo Comparator
Will receive placebo before spinal anesthesia
干预措施: Placebo (Drug)
结局指标
主要结局
Incidence of spinal hypotension
时间窗: After spinal anesthesia till delivery
Decrease systolic blood pressure \< 20% of baseline value
次要结局
- Time to first hypotensive episode(after induction of spinal anesthesia)
- Incidence of severe hypotension(After onset of spinal anesthesia)
- APGAR score(at 5 minutes after delivery)
- Umbilical artery pH(At 5 minutes after delivery)
研究者
Mina Adolf Helmy
Lecturer of anesthesia and critical care
Cairo University
研究点 (1)
Loading locations...
相似试验
招募中
1 期
The preoperative oral caffeine for the prophylaxis against spinal anesthesia induced hypotension in patients undergoing orthopedic lower limb surgery: A randomized controlled studyCirculatory SystemOrthopaedicsAnaesthesiaPACTR202311786558285Mansoura university hospital120
招募中
2 期
Caffeine and spinal anestheis related hypotensioPACTR202101657899436anesthesia and intensive care department faculty of medicine menoufia university140
招募中
3 期
Effect of prophylactic Caffeine on duration of respiratory support in preterm neonates with RDSneonatal respiratory distress syndrome.Respiratory distress syndrome of newbornP22.0IRCT20170627034782N2Esfahan University of Medical Sciences45
已完成
不适用
Assessment of the effect of preoperative oral carbohydrate on agitation in childreHernia.Femoral herniaIRCT20170516033992N1Oroumia University of Medical Sciences120
尚未招募
3 期
Evffect of preoperative oral carbohydrate on the blood glucose in childreBlood glucose.Elevated blood glucose levelIRCT20170516033992N7Oroumia University of Medical Sciences207