Accommodation Training and Aberration Control in Myopia Development
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- Change in refractive error in myopia in 6 monthly intervals for 2 years
研究概览
简要总结
We have identified focussing problems related to myopia getting worse. Our trial uses optical and orthoptic interventions that correct the focussing problems to see if this retards myopia progression.
详细描述
Myopia is a burgeoning health and social problem. Currently there is no acceptable clinical treatment that prevents progression. This study is a double masked placebo controlled block randomized clinical trial of two interventions, to treat accommodative factors we have identified as being significantly correlated to myopia progression (rather than to the presence of myopia). We have shown that the interventions normalise the accommodative factors, and this trial examines the effect of these interventions on myopia progression.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- Double
入排标准
- 年龄范围
- 14 Years 至 21 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Best corrected visual acuity of 6/5 in each eye
- •Myopia in each meridian of at least 0.50 D
- •Willingness to give consent
- •Willingness to undertake any treatment option
排除标准
- •History of systemic/ocular pathology
- •History of any ocular surgery
- •More than 10D of myopia
- •Astigmatism more than 1.00 D
结局指标
主要结局
Change in refractive error in myopia in 6 monthly intervals for 2 years
Change in axial length in 6 monthly intervals for 2 years
Age effects on refractive changes over 2 years
次要结局
- Change in accommodative response in 6 monthly intervals for 2 years
- Change in accommodative facility in 6 monthly intervals for 2 years
- Change in peripheral refraction in 6 monthly intervals for 2 years
- Change in AC/A ratio in 6 monthly intervals for 2 years