Time-lapse monitoring in IVF and ICSI patients
Completed
- Conditions
- Subfertility
- Registration Number
- NL-OMON24583
- Lead Sponsor
- VU University Medical Center Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 1740
Inclusion Criteria
Women scheduled for a single embryo transfer (SET) during their first IVF or ICSI cycle at any of the participating IVF centers will be considered for inclusion.
Exclusion Criteria
Patients with a double embryo transfer, a planned ‘freeze all’ cycle without a fresh embryo transfer, or participation in an interfering scientific study will not be included in the study. Patients who are treated with donor sperm or
donor oocytes will be excluded. Also patients scheduled for PGD or thawing of
oocytes after vitrification will be excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study parameters are the ongoing pregnancy rate of the first fresh<br><br>SET and the cumulative ongoing pregnancy rate including the first fresh SET<br><br>and all subsequent cryo transfers from the same ovum pick up cycle within<br><br>one year.
- Secondary Outcome Measures
Name Time Method The following secondary and exploratory endpoints will be analyzed:<br><br>biochemical pregnancy rate and live birth rate after fresh SET, cumulative live<br><br>birth rate, miscarriage rate, time to pregnancy, embryo morphology and<br><br>number of usable embryos (ie embryos used for transfer or<br><br>cryopreservation), morphokinetic parameters, pregnancy rates in three<br><br>female age groups, cost-efficiency, outcome of manual time-lapse<br><br>annotations.