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A Biological Sample Collection Protocol of Women With and Without Breast Cancer

Completed
Conditions
Breast Cancer
Registration Number
NCT00472589
Lead Sponsor
Hoosier Cancer Research Network
Brief Summary

The purpose of this trial is to collect plasma, serum, whole blood and tissue samples from women with breast cancer and plasma, serum, whole blood from healthy women, which will be made available to researchers for biomarker analysis.

Detailed Description

OUTLINE: This is a multi-center study.

The treatment plan for each breast cancer subject will be determined at the discretion of the treating physician and subject. This protocol does not prescribe any particular standard of care treatment.

There will be no treatment for the healthy volunteers.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
400
Inclusion Criteria

FOR WOMEN WITH BREAST CANCER

  • Histologically or cytologically confirmed invasive malignancy or ductal carcinoma in situ of the breast.
  • Preparing to begin a new regimen for breast cancer (adjuvant, locally recurrent, any line metastatic).
  • Female.
  • Age > 18 years at the time of consent.
  • Written informed consent and HIPAA authorization for release of personal health information.

FOR HEALTHY VOLUNTEERS

  • No known history of invasive malignancy or ductal carcinoma in situ. Volunteers must not have prior history of malignancy in the past 5 years with the exception of basal cell and squamous cell carcinoma of the skin. Other cancers with low potential for metastasis, such as in situ cancers (e.g., Grade 1, TA TCC (low grade superficial bladder cancer), colonic polyp with focus of adenocarcinoma) can also be enrolled as healthy volunteers.
  • Female
  • Age > 18 years at the time of consent.
  • Written informed consent and HIPAA authorization for release of personal health information.
Exclusion Criteria
  • Females must not be pregnant.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (11)

Indiana University Cancer Center

🇺🇸

Indianapolis, Indiana, United States

Quality Cancer Center (MCGOP)

🇺🇸

Indianapolis, Indiana, United States

Oncology Partners Network

🇺🇸

Cincinnati, Ohio, United States

Horizon Oncology Center

🇺🇸

Lafayette, Indiana, United States

Fort Wayne Oncology & Hematology, Inc

🇺🇸

Fort Wayne, Indiana, United States

Medical & Surgical Specialists, LLC

🇺🇸

Galesburg, Illinois, United States

Cancer Care Center of Southern Indiana

🇺🇸

Bloomington, Indiana, United States

Oncology Hematology Associates of SW Indiana

🇺🇸

Evansville, Indiana, United States

Arnett Cancer Care

🇺🇸

Lafayette, Indiana, United States

Northern Indiana Cancer Research Consortium

🇺🇸

South Bend, Indiana, United States

Medical Consultants, P.C.

🇺🇸

Muncie, Indiana, United States

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