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Clinical Trials/NCT01917305
NCT01917305
Completed
Not Applicable

Influence of Platform-switching on Bone Level Alterations: a 3 Year RCT.

Søren Jepsen0 sites25 target enrollmentFebruary 2007

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Periimplant Crestal Bone Level Changes
Sponsor
Søren Jepsen
Enrollment
25
Primary Endpoint
Change of vertical implant bone level
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The concept of platform-switching has been introduced to implant dentistry based on clinical observations of reduced periimplant crestal bone loss. However, published available data are controversial and most studies are limited to 12 months. The aim of the present RCT was to test the hypothesis that platform-switching has a positive impact on crestal bone level changes after 3 years.

Detailed Description

Two implants with a diameter of 4 mm were inserted crestally in the posterior mandible of 25 subjects. After three months of submerged healing, single-tooth crowns were randomly placed, either with (3.3mm platform, test) or without platform-switching (4mm platform, control). Patients were followed up at short intervals for monitoring of healing an oral hygiene. Statistical analysis for the influence of time and platform-type on bone levels employed the Brunner-Langer Model.

Registry
clinicaltrials.gov
Start Date
February 2007
End Date
March 2010
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor Investigator
Principal Investigator

Søren Jepsen

Professor Dr.med Dr. med.dent MS, Chair

University Hospital, Bonn

Eligibility Criteria

Inclusion Criteria

  • good general health
  • edentulous gap in the posterior mandible for placement of 2 implants
  • sufficient bone height above the alveolar nerve for placement of implants with a height of 9.5mm
  • bone width for placement of implants with diameter of 4mm
  • at least 4mm keratinized mucosa
  • medium or a thick soft tissue biotype

Exclusion Criteria

  • infectious disease
  • diabetes or osteopathy
  • active periodontitis
  • medication influencing bone metabolism
  • lactating or pregnant women

Outcomes

Primary Outcomes

Change of vertical implant bone level

Time Frame: Implant insertion (baseline), 3 months (reopening), 4 months (crown mounting), 12, 25 and 38 months

Secondary Outcomes

  • Plaque(baseline, 4, 8, 12, 25, 38 months)
  • probing depths(4, 8, 12, 25, 38 months)
  • Bleeding(baseline, 4, 8, 12, 25, 38 months)

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