Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Number of participants with increase in insula anterior cingulate cortex signal on magnetic resonance imaging
研究概览
简要总结
Functional magnetic resonance imaging in women with chronic pelvic pain using arterial spin labelling, functional connectivity, diffusion tensor imaging and magnetic resonance spectroscopy.
详细描述
Multimodal magnetic resonance neuroimaging will be utilised. Arterial spin labelling is tightly coupled with cerebral metabolism and can be used as a marker of neural activity. Resting state magnetic resonance imaging which measures synchronous activity across the brain, allows detection of functional connectivity of intrinsic brain network. Diffusion tensor imaging detects the anisotropic water diffusion in axonal fibres can provide information on connectivity and fibre tracts. Magnetic resonance spectroscopy would enable the levels of neurotransmitter to be elucidated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Chronic pelvic pain
- •Endometriosis
排除标准
- •Contraindication to magnetic resonance imaging
研究组 & 干预措施
Magnetic resonance imaging
Functional magnetic resonance imaging using arterial spin labelling, functional connectivity, diffusion tensor imaging, magnetic resonance spectroscopy to evaluate women with chronic pelvic pain and/ or endometriosis
干预措施: Functional magnetic resonance imaging (Other)
结局指标
主要结局
Number of participants with increase in insula anterior cingulate cortex signal on magnetic resonance imaging
时间窗: 1 hour
Magnetic resonance imaging using arterial spin labelling, functional connectivity, diffusion tensor imaging, magnetic resonance imaging
次要结局
- Number of subjects in psychological testing with increased anxiety, depression and pain catastrophizing scores(1 hour)
研究者
Sng Ban Leong
Principal Investigator
KK Women's and Children's Hospital