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Motor cortical control of antagonist muscle function in aging

Conditions
Elderly
Registration Number
NL-OMON23489
Lead Sponsor
niversity Medical Center Groningen (UMCG)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
28
Inclusion Criteria

Healthy younger adults aged 18 - 30 years and healthy older adults aged 65 years and older, both male and female gender, right handed based on the Edinburgh Handedness Inventory.

Exclusion Criteria

Fracture in the upper extremity over the past year, neurological disorders, pregnancy, muscle or joint disorders, cardiovascular diseases, medicine known to affect nerve conduction, Epilepsy, Pacemaker, metal in the brain/skull.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The amount of coactivation during a rapid flexion of the wrist after hearing an auditory tone
Secondary Outcome Measures
NameTimeMethod
The corticospinal excitability indexed by the size of the motor evoked potentials (MEPs) produced by transcranial magnetic stimulation (TMS)
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