The effect of chemotherapy in rectal cancer
Phase 3
Recruiting
- Conditions
- Rectal cancer.Malignant neoplasm of rectum
- Registration Number
- IRCT20200803048281N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
All patients with pathologically confirmed rectal cancer who are in locally advanced stage based on imaging
Exclusion Criteria
Patients diagnosed with Renal disease who are not candidates for chemotherapy or need to adjust the dose
Patients diagnosed with hepatic disease who are not candidates for chemotherapy or need to adjust the dose
Patients diagnosed with Cardiovascular disease who are not candidates for chemotherapy
Patients with underlying colorectal disease such as Crohn's disease or ulcerative collitis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pathologic Complete response to treatment. Timepoint: Before the surgery. Method of measurement: Based on preoperative history, examination and imaging.;Pathologic Complete response to treatment. Timepoint: After the surgery. Method of measurement: Based on the surgical pathology report.
- Secondary Outcome Measures
Name Time Method