The role of the pulmonary vasculature in the Fontan circulation - Fontan HC

niversitair Medisch Centrum Groningen0 个研究点目标入组 25 人开始时间: 待定最近更新: 2024年6月18日

适应症

试验速览

暂无简介。

•Fontan group:
•- written informed consent
•- Patients who underwent a TCPC/Fontan procedure
•- Follow-up at UMCG
•- adult 18 years or older
•- Clinical indication for cardiac catheterization;Control group:
•- written informed consent
•- absence of Fontan circulation or univentricular heart-like diagnosis
•- Follow-up at UMCG
•- adult 18 years or older
•- clinical indication for right heart catheterization
•- absence of pulmonary vascular diseases
•- normal pulmonary vascular hemodynamic profile;PAH group
•- Written informed consent
•- Clinical indication for right heart catheterization
•- History of pulmonary arterial hypertension [PAH] diagnosis (criteria; mean pulmonary artery pressure > 25mmHg, pulmonary capillary wedge pressure <15mmHg, pulmonary vascular resistance index > 3 wood units, and other possible causes for pulmonary hypertension excluded).
•- Reconfirmation of PAH diagnosis based on hemodynamic criteria during the right heart catheterization.

•Fontan group:
•- Standard exclusion criteria for cardiac catheterization
•- Obstruction in Fontan conduit
•- Inability to measure a reliable cardiac index and PVR (rhythm instability, hemodynamic or anatomic reasons);Control group:
•- No specific exclusion criteria apart from the standard exclusion criteria for right heart catheterization;PAH group
•- No specific exclusion criteria apart from the standard exclusion criteria for right heart catheterization.
•- Inability to perform a pulmonary OCT measurement during right catheterization (rhythm instability, hemodynamic or anatomic reasons)

发起方