Molecular pathological changes in the duodenal mucosa in patients with diabetes or functional dyspepsia - Molecular pathological changes in the duodenal mucosa in patients with diabetes or functional dyspepsia

Hyogo College of Medicine0 个研究点目标入组 60 人开始时间: 2017年10月1日最近更新: 2023年10月17日

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•1) Patients with malignant diseases, gastrointestinal-organic diseases (malignancies, peptic ulcers, esophagitis, etc.) or systemic diseases (neurological disease such as Parkinson disease or metabolic diseases except for diabetes). 2) Patients with a history of surgery of the upper gastrointestinal tract (stomach and esophagus). 3) Patients with severe liver dysfunction and renal dysfunction. 4) Patients with mental disorder. 5) A pregnant woman, nursing mother or the subjects who hope pregnancy during this study term. 6) Patients whom doctors judged unsuitable as objects for this study. 7) Patients with H. pylori eradication within 6 months. 8) Patients having the following medicines: prokinetic drugs, H2 blocker, proton pump inhibitor, gastric-mucosal protectant, prostaglandin, NSAIDs, anti-depressants, anti-anxiety agents, sleep inducer, anti-psychotics drugs. However, the patients, who can discontinue those medicines for two or more weeks before study start, can participate in this study.

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