MedPath

Mindfulness-Based Trauma Recovery for Refugees (MBTR-R)

Phase 1
Completed
Conditions
Stress Related Disorder
Stress Disorders, Post-Traumatic
Interventions
Behavioral: Mindfulness-Based Trauma Recovery for Refugees (MBTR-R)
Registration Number
NCT04380259
Lead Sponsor
University of Haifa
Brief Summary

Worldwide, refugees and asylum seekers suffer at high rates from trauma- and stress-related mental health problems. The investigators thus developed Mindfulness-Based Trauma Recovery for Refugees (MBTR-R) - a 9-week, mindfulness- and compassion-based, trauma-sensitive and socio-culturally adapted, group intervention for refugees and asylum seekers. The overarching aims of the study were to, first, test whether MBTR-R is an efficacious and safe mental health intervention for traumatized refugees and asylum seekers with respect to stress- and trauma-related mental health outcomes; and, second, to test theorized mechanisms of action of MBTR-R. Accordingly, the investigators conducted a randomized waitlist-controlled trial among a community sample of female and male Eritrean asylum seekers in an urban post-displacement setting in the Middle East (Israel).

Detailed Description

Broadly, the investigators aimed to assess whether MBTR-R is an efficacious and safe mental health intervention for traumatized asylum seekers. Aim I: The investigators predicted that, relative to a waitlist control condition, MBTR-R will lead to improved stress-and trauma-related mental health outcomes, including lower levels and rates of posttraumatic stress, depression, anxiety, and improved subjective well-being at post-intervention and 5-week follow-up. Aim II: The investigators aimed to test, whether relative to the waitlist-control condition, MBTR-R was safe and thus not associated with participant-level clinically significant deterioration in any of the monitored primary mental health outcomes at post-intervention or at follow-up. In the event of adverse responding, the investigators planned to test whether key demographic factors or pre-existing vulnerability factors at pre-intervention that may predict participant-level deterioration or adverse responding to the intervention - so as to identify candidate contraindications for MBTR-R. Aim III: The investigators predicted that, relative to a waitlist control condition, MBTR-R will lead to changes in psycho-behavioral processes targeted by the intervention and implicated in vulnerability at pre-intervention, from pre-to-post intervention, measured in controlled behavioral and cognitive-experimental lab tasks or experience sampling measures, including measures of (a) self-compassion and self-criticism, (b) self-referential processing of fear, (c) avoidance, (d) emotional reactivity to trauma-related information and autobiographical memory, (e) impaired executive functions of trauma-related information processing in working memory. Aim IV: The investigators aimed to test whether, among the MBTR-R group, pre-to-post-intervention change and pre-intervention to follow-up change in mental health outcomes (Aim I) will be predicted or mediated by pre-to-post intervention change in the targeted psycho-behavioral processes.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
158
Inclusion Criteria
  • Eritrean refugee or asylum seeker living in Israel
Exclusion Criteria
  • active suicidality
  • current psychotic symptoms
  • current mental health treatment (e.g. psychotherapy, participation in psycho-social support group)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
MBTR-R (Mindfulness-Based Trauma Recovery for Refugees)Mindfulness-Based Trauma Recovery for Refugees (MBTR-R)Mindfulness-based group intervention consisting of nine 2.5-hour weekly sessions.
Primary Outcome Measures
NameTimeMethod
Brief Patient Health Questionnaire (PHQ-9)Change from 1-week pre-intervention to 1-week post-intervention and change from 1-week pre-intervention to 5-weeks post-intervention

The brief Patient Health Questionnaire (PHQ-9) is a 9-item self-report questionnaire to assess depression symptom severity (5-point Likert scale) with higher scores indicating greater depression symptom severity (minimum scale score 0 and maximum scale score 36), PHQ-9 mean cut-off score ≥10 is commonly used to identify categorical (diagnostic) symptom status of depression

Beck's Anxiety Inventory (BAI)Change from 1-week pre-intervention to 1-week post-intervention and change from 1-week pre-intervention to 5-weeks post-intervention

The Beck's Anxiety Inventory (BAI) is a 21-item self-report questionnaire to assess anxiety symptom severity (4-point Likert scale) with higher scores indicating greater anxiety symptom severity (minimum scale score 0 and maximum scale score 63), BAI total cut-off score ≥ 16 is commonly used to identify categorical (diagnostic) symptom status of anxiety disorder

Harvard Trauma Questionnaire (HTQ)Change from 1-week pre-intervention to 1-week post-intervention and change from 1-week pre-intervention to 5-weeks post-intervention

The Harvard Trauma Questionnaire (HTQ) is a 16-item self-report questionnaire to assess post-traumatic stress symptom severity (5-point Likert scale) with higher scores indicating greater post-traumatic stress severity (minimum scale score 1 and maximum scale score 5), HTQ mean cut-off score ≥ 2 is commonly used to identify categorical (diagnostic) symptom status of post-traumatic stress disorder

Secondary Outcome Measures
NameTimeMethod
Autobiographical Memory Recall Task1-week pre-intervention, 1-week post-intervention

The Autobiographical Memory Recall Task measures avoidance in response to recalling a traumatic autobiographical memory

Post-Migration Living Difficulties Checklist (PMLD)1-week pre-intervention

The Post-Migration-Living-Difficulties Checklist (PMLD) is a 9-item self-report questionnaire to assess post-migration stress (5-point Likert scale) with higher scores indicating greater post-migration stress (minimum scale score 1 and maximum scale score 5)

Moral Injury Event Scale1-week pre-intervention, 1-week post-intervention and 5-weeks post-intervention

The Moral Injury Event Scale is a self-report questionnaire to assess moral injury (6-point Likert scale) with higher scores indicating greater levels of moral injury (minimum scale score 1 and maximum scale score 6)

Adapted Sternberg Working Memory Task1-week pre-intervention, 1-week post-intervention

The Adapted Sternberg Working Memory Task measures working memory processing of trauma- and stress-related words versus positive words

Self-Referential Encoding Task (SRET) of Self-Compassion and Self-Criticism1-week pre-intervention, 1-week post-intervention

The SRET measures self-referential processing of self-criticism and self-compassion

Single Experience and Self-Implicit Association Task (SES-IAT)1-week pre-intervention, 1-week post-intervention

The SES-IAT measures self-referential processing of fear

Experience Sampling of State Mindfulness15-minutes pre-intervention session and 15-minutes post-intervention session

3-item experience sample (5-point Likert scale) of state mindfulness (minimum score 3 maximum score 15), higher scores indicate greater levels of state mindfulness

The State Shame and Guilt Scale (SSGS)1-week pre-intervention, 1-week post-intervention and 5-weeks post-intervention

The State Shame and Guilt Scale (SSGS) is a 15-item self-report questionnaire to assess state shame and guilt (5-point Likert scale) with higher scores indicating greater levels of state shame, guilt and pride (minimum scale score 15 and maximum scale score 75)

The Five Facets Mindfulness Questionnaire (FFMQ)1-week pre-intervention, 1-week post-intervention and 5-weeks post-intervention

The Five Facets of Mindfulness Questionnaire (FFMQ) is a self-report questionnaire to assess different facets of trait mindfulness (5-point Likert scale) with higher scores indicating greater levels of trait mindfulness (minimum scale score 1 and maximum scale score 5)

Experience Sampling of Depression15-minutes pre-intervention session

1-item experience sample (5-point Likert scale) of depression (minimum score 1 maximum score 5), higher scores indicate greater levels of depression

Brief Inventory of Thriving (BIT)1-week pre-intervention, 1-week post-intervention and 5-weeks post-intervention

One item of the 9-item self-report questionnaire Brief Inventory of Thriving (BIT) was used to assess subjective well-being (5-point Likert scale) with higher scores indicating greater subjective well-being (minimum score 1 and maximum score 5)

Trauma Cue Exposure Task1-week pre-intervention, 1-week post-intervention

The Trauma Cue Exposure Task measures behavioral avoidance in response to trauma cues

Experience Sampling of Negative Repetitive Thinking15-minutes pre-intervention session

1-item experience sample (5-point Likert scale) of negative repetitive thinking (minimum score 1 maximum score 5), higher scores indicate greater levels of negative repetitive thinking

Experience Sampling of Emotion15-minutes pre-intervention session and 15-minutes post-intervention session

4-item experience sample (5-point Likert scale) of the emotions happy, calm, sad and nervous/tense (minimum score 4 maximum score 20), higher scores indicate greater levels of the emotions happy, calm, sad and nervous/tense

The Short Self Compassion Scale (SSCS)1-week pre-intervention, 1-week post-intervention and 5-weeks post-intervention

The Short Self-Compassion Scale SSCS is a 12-item self-report questionnaire to assess different facets of self-compassion (5-point Likert scale) with higher scores indicating greater levels of self-compassion (minimum scale score 1 and maximum scale score 5)

Experience Sampling of Cognitive Avoidance15-minutes pre-intervention session

1-item experience sample (5-point Likert scale) of cognitive avoidance (minimum score 1 maximum score 5), higher scores indicate greater levels of cognitive avoidance

Experience Sampling of Self-Compassion15-minutes pre-intervention session

1-item experience sample (5-point Likert scale) of negative self-compassion (minimum score 1 maximum score 5), higher scores indicate greater levels of self-compassion

Experience Sampling of Formal and Informal Mindfulness Practice15-minutes pre-intervention session

2-item experience sample number of formal and informal mindfulness practice during the past week, higher scores indicate greater number of mindfulness practices during the past week

Experience Sampling of Anxiety15-minutes pre-intervention session

1-item experience sample (5-point Likert scale) of anxiety (minimum score 1 maximum score 5), higher scores indicate greater levels of anxiety

Trial Locations

Locations (1)

Kuchinate

🇮🇱

Tel Aviv, Merkaz, Israel

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