Treadmill Training is an Effective Rehabilitation Program in Treatment of Children With Acute Lymphoblastic Leukemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Tandem Walk (TW)
研究概览
简要总结
Purpose: The present research was conducted to study the effect of treadmill training on balance after chemotherapy in children with acute lymphoblastic leukemia.
Subjects and Methods: Forty children with acute lymphoblastic leukemia included in the current research ranged of age from 8 to 12 years. The children participated in this study were assigned randomly into two equal number groups (A and B). Group (A) includes 20 children who received balance exercises, while group (B) includes 20 children who received the same balance exercises of group (A) and treadmill training. The treatment program was applied three sessions per week (60 min for every session) for 8 weeks. Balance Master System and Biodex Balance System were used to evaluate balance of all children in the three groups before and after the treatment program.
详细描述
The current research is a randomized control trial to differentiate between the treadmill training on balance after chemotherapy in children with acute lymphoblastic leukemia. Chemotherapy induced peripheral neuropathy is related to the intensity of treatment and dosage of chemotherapy which could affect the severity of its symptoms, it could result in serious problems like sensory changes and numbness , in case the sensory nerves were affected , muscle weakness and in-coordination in case the affected were the motor nerves. In addition to the psychological problems the patient experience as a result of CIPN, the patient also experience physical problems like injuries, fear of fall results from lack of sensory perception and muscle power. Treadmill training, motor training may favor proprioceptive feedback, leading to adjustments for adequate postural balance and functional performance. Treadmill exercises stimulate the kinetic, kinematic, and temporal features of walking. These exercises improve the strength of the muscles of the lower extremities, enhance motor learning, improve functional abilities, and activate the locomotor control system
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 8 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •able to recognize commands given to them,
- •understand our verbal command and encouragement,
- •and stand and walk independently without repeated falling
排除标准
- •Children with impairment of sensation or
- •other neurological or psychological problems,
- •tightness and/or fixed deformity of lower limbs,
- •any neurological, musculoskeletal, or mobility disorders,
- •cardiac anomalies,
- •vision or hearing loss
研究组 & 干预措施
Balance exersices group
received traditional exercise program with instructions given to the children for 60 min aiming to improve posture control and balance
干预措施: Balance exrcises (Other)
Balance exersices and treadmill group
received the same traditional physical therapy program as the same applied in group of balance exercise (30 min), in addition to treadmill training (30 min)
干预措施: Balance exrcises and Treadmill training (Other)
结局指标
主要结局
Tandem Walk (TW)
时间窗: 2 months
to measure Speed (cm/sec)
Step/Quick Turn (SQT)
时间窗: 2 months
Turn Time (sec) from right and left side
Step/Quick Turn
时间窗: 2 months
Turn Sway (deg/sec) from right and left side
Overall Stability Index
时间窗: 2 months
from Biodex Balance System
Medio-lateral Stability Index
时间窗: 2 months
from Biodex Balance System
Antero-posterior Stability Index
时间窗: 2 months
from Biodex Balance System
次要结局
未报告次要终点
研究者
Reham Saeed Alsakhawi
Assistant Professor
Cairo University