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临床试验/NCT05032716
NCT05032716已完成不适用

Treadmill Training is an Effective Rehabilitation Program in Treatment of Children With Acute Lymphoblastic Leukemia

Cairo University3 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2021年5月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
3
主要终点
Step/Quick Turn

研究概览

简要总结

Purpose: The present research was conducted to study the effect of treadmill training on balance after chemotherapy in children with acute lymphoblastic leukemia.

Subjects and Methods: Forty children with acute lymphoblastic leukemia included in the current research ranged of age from 8 to 12 years. The children participated in this study were assigned randomly into two equal number groups (A and B). Group (A) includes 20 children who received balance exercises, while group (B) includes 20 children who received the same balance exercises of group (A) and treadmill training. The treatment program was applied three sessions per week (60 min for every session) for 8 weeks. Balance Master System and Biodex Balance System were used to evaluate balance of all children in the three groups before and after the treatment program.

详细描述

The current research is a randomized control trial to differentiate between the treadmill training on balance after chemotherapy in children with acute lymphoblastic leukemia. Chemotherapy induced peripheral neuropathy is related to the intensity of treatment and dosage of chemotherapy which could affect the severity of its symptoms, it could result in serious problems like sensory changes and numbness , in case the sensory nerves were affected , muscle weakness and in-coordination in case the affected were the motor nerves. In addition to the psychological problems the patient experience as a result of CIPN, the patient also experience physical problems like injuries, fear of fall results from lack of sensory perception and muscle power. Treadmill training, motor training may favor proprioceptive feedback, leading to adjustments for adequate postural balance and functional performance. Treadmill exercises stimulate the kinetic, kinematic, and temporal features of walking. These exercises improve the strength of the muscles of the lower extremities, enhance motor learning, improve functional abilities, and activate the locomotor control system

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
8 Years 至 12 Years(Child)
性别
All
接受健康志愿者

入选标准

  • able to recognize commands given to them,
  • understand our verbal command and encouragement,
  • and stand and walk independently without repeated falling

排除标准

  • Children with impairment of sensation or
  • other neurological or psychological problems,
  • tightness and/or fixed deformity of lower limbs,
  • any neurological, musculoskeletal, or mobility disorders,
  • cardiac anomalies,
  • vision or hearing loss

结局指标

主要结局

Step/Quick Turn

时间窗: 2 months

Turn Sway (deg/sec) from right and left side

Overall Stability Index

时间窗: 2 months

from Biodex Balance System

Medio-lateral Stability Index

时间窗: 2 months

from Biodex Balance System

Step/Quick Turn (SQT)

时间窗: 2 months

Turn Time (sec) from right and left side

Antero-posterior Stability Index

时间窗: 2 months

from Biodex Balance System

Tandem Walk (TW)

时间窗: 2 months

to measure Speed (cm/sec)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Reham Saeed Alsakhawi

Assistant Professor

Cairo University

研究点 (3)

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