Neurocognitive Enhancement in Major Depressive Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 2
- 主要终点
- Performance on paper and pencil assessments of neurocognition after treatment, compared to baseline assessment performance
研究概览
简要总结
The purpose of this study is to examine the effects of neurocognitive enhancement on cognitive abilities and related social and adaptive behaviours in individuals diagnosed with major depressive disorder. Subjects in this study will be randomized to receive Neurocognitive Enhancement Therapy (NET) or to a wait list and then NET . Secondary aims include examining whether the cognitive benefits are potentiated by repeated exposure during in-home practice with complementary exercises. Additionally, the investigators will examine the durability of the effects and their generalization to functional capacity and everyday functional performance after completion of the groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or Female.
- •Subjects will be between the ages of 18 and 65, which is the age range with available normative comparison data.
排除标准
- •Presence of a medical diagnosis that is associated with known cognitive impairments, such as multiple sclerosis, cerebrovascular accident, dementia, or history of traumatic brain injury.
- •Subjects with a reading level below grade 6, as assessed with the Wide Range Achievement Test - Reading Recognition Subtest, will be excluded because of the likelihood of not understanding task instructions.
- •Subjects with uncorrectable vision or hearing impairment that would preclude valid assessments or intervention procedures.
结局指标
主要结局
Performance on paper and pencil assessments of neurocognition after treatment, compared to baseline assessment performance
时间窗: 20 weeks
次要结局
未报告次要终点
研究者
Christopher Bowie
Ph.D.
Queen's University