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临床试验/NCT04716582
NCT04716582Unknown不适用

The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity

Maastricht University1 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2019年6月7日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
21
试验地点
1
主要终点
Cognitive processes as assessed using Trail making test

研究概览

简要总结

Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively. For physical health evidence grows that short light intense interruptions of sitting time effectively counterbalance the impact of prolonged sitting. It is not clear of light intense physical activity breaks have a similar positive effect on cognitive performance. Also, it is unclear whether cognitive loading might be able to compensate the impact of prolonged sitting.This study compares the effects of uninterrupted sitting with or without cognitive loading and interrupted sitting on cognitive functioning; muscle activation of leg and trunk muscles under various modes of sitting with walking, in order to calibrate the physical impact of different sitting modes.

详细描述

healthy university students will attend three separate intervention visits with 6-days (no more than 14 days) washout in between: 1) uninterrupted sitting (SIT); 2) uninterrupted sitting with a cognitive task (COGN); 3) sitting interrupted by light physical activity (INTERRUPT). For the SIT and INTERRUPT conditions, subjects watch a series of documentaries while sitting. In the COGN condition, while sitting, participants undergo the online GED test as cognitive load. Four cognitive tests (D2 test, stroop test, trail making test and 2-BACK test) and mood states will be performed before and after each intervention. On a separate day, using surface electromyography, activations of major leg and trunk muscles of sitting on chair, active and passive sitting on a yoga ball and walking were assessed.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •age 18-30 years
  • •BMI between 18-28
  • •steady dietary habits
  • •generally healthy
  • •Female on contraceptive pills/Male

排除标准

  • •High score (score: 11-21) in the Hospital Anxiety and Depression Scale

研究组 & 干预措施

SIT group

Experimental

participants will sitting 4 hours continuously.

干预措施: uninterrupted sitting (Behavioral)

INTERRUPT group

Experimental

participants will sitting 25 minutes with 5 minutes walking per half hour,40minutes walking in total

干预措施: Sitting interrupted by light physical activity (Behavioral)

COGN group

Experimental

participants will perform GED test as cognitive loading task during 4-hour sitting

干预措施: Sitting with cognitive task (Behavioral)

结局指标

主要结局

Cognitive processes as assessed using Trail making test

时间窗: change from baseline after 4 hour intervention on day1, day8, day16

Trail making test is a computer-based test to assess task-switching. reaction time and accuracy of the trail making test will be collected before and after the intervention.

Cognitive processes as assessed using D2 attention test

时间窗: change from baseline after 4 hour intervention on day1, day8, day16

D2 attention test is a paper and pencil test to assess attention. Concentration performance will be collected before and after the intervention.

Cognitive processes as assessed using Stroop test

时间窗: change from baseline after 4 hour intervention on day1, day8, day16

Stroop test is a computer-based Stroop word and color test, including congruent trials and incongruent trials to assess inhibition. Reaction time and accuracy of the Stroop test will be collected before and after the intervention

Cognitive processes as assessed using N back test

时间窗: change from baseline after 4 hour intervention on day1, day8, day16

N back test is a computer-based test, including target images and non-target images. this test is for updating and working memory. The correct reaction number of N back test will be collected before and after the intervention.

次要结局

  • mood status assessed by depression score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by esteem-related effect score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by total mood level score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by tension score(change from baseline after 4 hour intervention on day1, day8, day16)
  • mood status assessed by confusion score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by fatigue score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • discomfort level(report discomfort level immediately after each sitting condition(each sitting posture lasts 5 minutes).it will be performed on another experiment day.)
  • mood status assessed by vigor score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by anger score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • muscle activity(recording 5 minutes' muscle activity for each sitting posture, average RMS will be collected.it will be performed on another experiment day.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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