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Clinical Trials/NCT04716582
NCT04716582
Unknown
Not Applicable

The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity

Maastricht University1 site in 1 country21 target enrollmentJune 7, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sedentary Behavior
Sponsor
Maastricht University
Enrollment
21
Locations
1
Primary Endpoint
Cognitive processes as assessed using Trail making test
Last Updated
5 years ago

Overview

Brief Summary

Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively. For physical health evidence grows that short light intense interruptions of sitting time effectively counterbalance the impact of prolonged sitting. It is not clear of light intense physical activity breaks have a similar positive effect on cognitive performance. Also, it is unclear whether cognitive loading might be able to compensate the impact of prolonged sitting.This study compares the effects of uninterrupted sitting with or without cognitive loading and interrupted sitting on cognitive functioning; muscle activation of leg and trunk muscles under various modes of sitting with walking, in order to calibrate the physical impact of different sitting modes.

Detailed Description

healthy university students will attend three separate intervention visits with 6-days (no more than 14 days) washout in between: 1) uninterrupted sitting (SIT); 2) uninterrupted sitting with a cognitive task (COGN); 3) sitting interrupted by light physical activity (INTERRUPT). For the SIT and INTERRUPT conditions, subjects watch a series of documentaries while sitting. In the COGN condition, while sitting, participants undergo the online GED test as cognitive load. Four cognitive tests (D2 test, stroop test, trail making test and 2-BACK test) and mood states will be performed before and after each intervention. On a separate day, using surface electromyography, activations of major leg and trunk muscles of sitting on chair, active and passive sitting on a yoga ball and walking were assessed.

Registry
clinicaltrials.gov
Start Date
June 7, 2019
End Date
May 30, 2021
Last Updated
5 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • age 18-30 years
  • BMI between 18-28
  • steady dietary habits
  • generally healthy
  • Female on contraceptive pills/Male

Exclusion Criteria

  • High score (score: 11-21) in the Hospital Anxiety and Depression Scale

Outcomes

Primary Outcomes

Cognitive processes as assessed using Trail making test

Time Frame: change from baseline after 4 hour intervention on day1, day8, day16

Trail making test is a computer-based test to assess task-switching. reaction time and accuracy of the trail making test will be collected before and after the intervention.

Cognitive processes as assessed using D2 attention test

Time Frame: change from baseline after 4 hour intervention on day1, day8, day16

D2 attention test is a paper and pencil test to assess attention. Concentration performance will be collected before and after the intervention.

Cognitive processes as assessed using Stroop test

Time Frame: change from baseline after 4 hour intervention on day1, day8, day16

Stroop test is a computer-based Stroop word and color test, including congruent trials and incongruent trials to assess inhibition. Reaction time and accuracy of the Stroop test will be collected before and after the intervention

Cognitive processes as assessed using N back test

Time Frame: change from baseline after 4 hour intervention on day1, day8, day16

N back test is a computer-based test, including target images and non-target images. this test is for updating and working memory. The correct reaction number of N back test will be collected before and after the intervention.

Secondary Outcomes

  • mood status assessed by depression score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by esteem-related effect score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by total mood level score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by tension score(change from baseline after 4 hour intervention on day1, day8, day16)
  • mood status assessed by confusion score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by fatigue score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • discomfort level(report discomfort level immediately after each sitting condition(each sitting posture lasts 5 minutes).it will be performed on another experiment day.)
  • mood status assessed by vigor score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • mood status assessed by anger score(change from baseline all mood outcomes after 4 hour intervention on day1, day8, day16)
  • muscle activity(recording 5 minutes' muscle activity for each sitting posture, average RMS will be collected.it will be performed on another experiment day.)

Study Sites (1)

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