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The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity

Not Applicable
Conditions
Light Intensity Physical Activity
Sedentary Behavior
Interventions
Behavioral: uninterrupted sitting
Behavioral: Sitting with cognitive task
Behavioral: Sitting interrupted by light physical activity
Registration Number
NCT04716582
Lead Sponsor
Maastricht University
Brief Summary

Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively. For physical health evidence grows that short light intense interruptions of sitting time effectively counterbalance the impact of prolonged sitting. It is not clear of light intense physical activity breaks have a similar positive effect on cognitive performance. Also, it is unclear whether cognitive loading might be able to compensate the impact of prolonged sitting.This study compares the effects of uninterrupted sitting with or without cognitive loading and interrupted sitting on cognitive functioning; muscle activation of leg and trunk muscles under various modes of sitting with walking, in order to calibrate the physical impact of different sitting modes.

Detailed Description

healthy university students will attend three separate intervention visits with 6-days (no more than 14 days) washout in between: 1) uninterrupted sitting (SIT); 2) uninterrupted sitting with a cognitive task (COGN); 3) sitting interrupted by light physical activity (INTERRUPT). For the SIT and INTERRUPT conditions, subjects watch a series of documentaries while sitting. In the COGN condition, while sitting, participants undergo the online GED test as cognitive load. Four cognitive tests (D2 test, stroop test, trail making test and 2-BACK test) and mood states will be performed before and after each intervention. On a separate day, using surface electromyography, activations of major leg and trunk muscles of sitting on chair, active and passive sitting on a yoga ball and walking were assessed.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
21
Inclusion Criteria
  • age 18-30 years
  • BMI between 18-28
  • steady dietary habits
  • generally healthy
  • Female on contraceptive pills/Male
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Exclusion Criteria
  • High score (score: 11-21) in the Hospital Anxiety and Depression Scale
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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
SIT groupuninterrupted sittingparticipants will sitting 4 hours continuously.
COGN groupSitting with cognitive taskparticipants will perform GED test as cognitive loading task during 4-hour sitting
INTERRUPT groupSitting interrupted by light physical activityparticipants will sitting 25 minutes with 5 minutes walking per half hour,40minutes walking in total
Primary Outcome Measures
NameTimeMethod
Cognitive processes as assessed using Trail making testchange from baseline after 4 hour intervention on day1, day8, day16

Trail making test is a computer-based test to assess task-switching. reaction time and accuracy of the trail making test will be collected before and after the intervention.

Cognitive processes as assessed using D2 attention testchange from baseline after 4 hour intervention on day1, day8, day16

D2 attention test is a paper and pencil test to assess attention. Concentration performance will be collected before and after the intervention.

Cognitive processes as assessed using Stroop testchange from baseline after 4 hour intervention on day1, day8, day16

Stroop test is a computer-based Stroop word and color test, including congruent trials and incongruent trials to assess inhibition. Reaction time and accuracy of the Stroop test will be collected before and after the intervention

Cognitive processes as assessed using N back testchange from baseline after 4 hour intervention on day1, day8, day16

N back test is a computer-based test, including target images and non-target images. this test is for updating and working memory. The correct reaction number of N back test will be collected before and after the intervention.

Secondary Outcome Measures
NameTimeMethod
mood status assessed by depression scorechange from baseline all mood outcomes after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

mood status assessed by esteem-related effect scorechange from baseline all mood outcomes after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

mood status assessed by total mood level scorechange from baseline all mood outcomes after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

mood status assessed by tension scorechange from baseline after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

mood status assessed by confusion scorechange from baseline all mood outcomes after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

mood status assessed by fatigue scorechange from baseline all mood outcomes after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

discomfort levelreport discomfort level immediately after each sitting condition(each sitting posture lasts 5 minutes).it will be performed on another experiment day.

after each sitting condition, self discomfort level will be asked.0 means no discomfort,10 means the worst discomfort

mood status assessed by vigor scorechange from baseline all mood outcomes after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

mood status assessed by anger scorechange from baseline all mood outcomes after 4 hour intervention on day1, day8, day16

mood questionnaire(an abbreviated version of Profile of Mood States (POMS)) will be used before and after the intervention, such as tension, anger, depression, vigor, esteem-related effect, confusion, fatigue, total mood level data included. The scale is 0 to 4.

muscle activityrecording 5 minutes' muscle activity for each sitting posture, average RMS will be collected.it will be performed on another experiment day.

Muscle activity is measured by the electromyograph (EMG)machine. RMS values will be collected and calculated as muscle activation during each sittings condition

Trial Locations

Locations (1)

Faculty of Health, Medicine and Life Sciences

🇳🇱

Maastricht, Limburg, Netherlands

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