A study to understand the healing of gum surgery with enzymes
- Conditions
- Health Condition 1: K055- Other periodontal diseases
- Registration Number
- CTRI/2024/02/062302
- Lead Sponsor
- Garapati Nitya sri
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients with persistent probing pocket depths of =5mm in at least four adjacent teeth (Periodontitis Stage II, III and Grade B, C)
1.Patients who have any active infections i.e., periapical, periodontal or odontogenic lesion
2.Any allergic reactions to the components of the systemic enzyme supplement
3.Severe congenital or acquired coagulation disorders (e.g. hemophilia, in dialysis patients) or liver damage,
4.Pregnancy or breastfeeding,
5.Any clinical signs or laboratory evidence for severe inflammatory, endocrine, renal/pulmonary, neurological, cardiovascular, metabolic, gastrointestinal, hematological, or psychiatric condition
6.Active malignancy of any type
7.Current use of anticoagulants or platelet aggregation inhibitors, chemotherapeutic agents, antibiotics, medication for lipids, diabetes, hypertension, inflammation, autoimmune diseases, mood disorders
8.Use of NSAID within 1 month of entering the study,
9.Alcoholism, smoking,
10.Current use of nutritional supplements
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Early wound healing score (EHS)Timepoint: T1-7days post surgically <br/ ><br>T2-14 days post surgically <br/ ><br>T3-30days post surgically
- Secondary Outcome Measures
Name Time Method Pain using Visual analog scale (VAS)Timepoint: T1-7 days post surgically <br/ ><br>T2-14 days post surgically <br/ ><br>T3-30 days post surgically