CTRI/2024/02/062302
Not yet recruiting
未知
Assessment of post-surgical healing and patient reported outcomes of adjunctive systemic enzyme therapy after periodontal flap surgery- A randomized clinical trial - Nil
Garapati Nitya sri0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: K055- Other periodontal diseases
- Sponsor
- Garapati Nitya sri
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients with persistent probing pocket depths of \=5mm in at least four adjacent teeth (Periodontitis Stage II, III and Grade B, C)
Exclusion Criteria
- •1\.Patients who have any active infections i.e., periapical, periodontal or odontogenic lesion
- •2\.Any allergic reactions to the components of the systemic enzyme supplement
- •3\.Severe congenital or acquired coagulation disorders (e.g. hemophilia, in dialysis patients) or liver damage,
- •4\.Pregnancy or breastfeeding,
- •5\.Any clinical signs or laboratory evidence for severe inflammatory, endocrine, renal/pulmonary, neurological, cardiovascular, metabolic, gastrointestinal, hematological, or psychiatric condition
- •6\.Active malignancy of any type
- •7\.Current use of anticoagulants or platelet aggregation inhibitors, chemotherapeutic agents, antibiotics, medication for lipids, diabetes, hypertension, inflammation, autoimmune diseases, mood disorders
- •8\.Use of NSAID within 1 month of entering the study,
- •9\.Alcoholism, smoking,
- •10\.Current use of nutritional supplements
Outcomes
Primary Outcomes
Not specified
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