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Clinical Trials/CTRI/2024/02/062302
CTRI/2024/02/062302
Not yet recruiting
未知

Assessment of post-surgical healing and patient reported outcomes of adjunctive systemic enzyme therapy after periodontal flap surgery- A randomized clinical trial - Nil

Garapati Nitya sri0 sites0 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Health Condition 1: K055- Other periodontal diseases
Sponsor
Garapati Nitya sri
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
Garapati Nitya sri

Eligibility Criteria

Inclusion Criteria

  • 1\. Patients with persistent probing pocket depths of \=5mm in at least four adjacent teeth (Periodontitis Stage II, III and Grade B, C)

Exclusion Criteria

  • 1\.Patients who have any active infections i.e., periapical, periodontal or odontogenic lesion
  • 2\.Any allergic reactions to the components of the systemic enzyme supplement
  • 3\.Severe congenital or acquired coagulation disorders (e.g. hemophilia, in dialysis patients) or liver damage,
  • 4\.Pregnancy or breastfeeding,
  • 5\.Any clinical signs or laboratory evidence for severe inflammatory, endocrine, renal/pulmonary, neurological, cardiovascular, metabolic, gastrointestinal, hematological, or psychiatric condition
  • 6\.Active malignancy of any type
  • 7\.Current use of anticoagulants or platelet aggregation inhibitors, chemotherapeutic agents, antibiotics, medication for lipids, diabetes, hypertension, inflammation, autoimmune diseases, mood disorders
  • 8\.Use of NSAID within 1 month of entering the study,
  • 9\.Alcoholism, smoking,
  • 10\.Current use of nutritional supplements

Outcomes

Primary Outcomes

Not specified

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