Analgesia Nociception Index and Autonomic Nervous System Exploration During Continuous Renal Replacement Therapy in Intensive Care Patients.

Hospices Civils de Lyon1 个研究点分布在 1 个国家目标入组 30 人2026年1月9日

适应症Critically Ill Renal Replacement Therapy

概览

阶段: 不适用
干预措施: 未指定
疾病 / 适应症: Critically Ill
发起方: Hospices Civils de Lyon
入组人数: 30
试验地点: 1
主要终点: Percentage of changes in ANI.
状态: 招募中
最后更新: 3个月前

概览研究者入排标准结局指标研究点相似试验

概览

简要总结

The Analgesia Nociception Index (ANI) reflects the balance between sympathetic and parasympathetic tone. It is based on a specific interpretation of the R-R interval variation. During fluid removal by net ultrafiltration in patients with fluid overload and continuous renal replacement therapy, some data suggest that haemodynamic variation could be induced by the autonomic nervous system. The study aims to investigate ANI variations in this context and their association with the haemodynamic variations observed.

注册库

clinicaltrials.gov

开始日期

2026年1月9日

结束日期

2027年4月1日

最后更新

3个月前

研究类型

Observational

性别

All

研究者

发起方

Hospices Civils de Lyon

责任方

Sponsor

入排标准

入选标准

•Continuous renal replacement therapy in intensive care unit
•Initiation of net ultrafiltration according to the protocol of the department or to EARLYDRY study (NCT 05817539) (3 criteria required):
•Fluid overload \> 5% or peripheral oedema
•Noradrenaline equivalent \<0.5μg/kg/min
•No peripheral hypoperfusion
•Invasive blood pressure monitoring
•Central venous line in superior vena cava territory
•Regular sinus rhythm
•Patient awake or Richmond Agitation and Sedation Scale \> -3