The Efficacy of Magnetic Stimulation in Patients with Major Depressive Disorder

Phase 3

Recruiting

• Conditions: Major Depressive Disorder Resistant to First-line Pharmaceutical Therapy.; F33; Major Depr

• Registration Number: IRCT20190612043877N1
• Lead Sponsor: Qazvin University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 27 June 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Inclusion criteria were the age of 18 to 70 years
Primary diagnosis of MDD by a psychiatrist based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders version V (DSM-V).
the patients whose MDD was approved by a specialist according to MDD criteria and who had received and failed to respond to an episode of treatment (for at least six weeks) with effective tolerated doses of antidepressants were included in the study. The patients should have received the same medication from six weeks to the onset of the study and continued taking the drug during the study.
Exclusion criteria comprised the presence of underlying diseases
History of rTMS treatment due to any disorder
History of seizures or neurosurgery,
Having a pacemaker
Pregnancy
Being diagnosed with a high risk of suicide, substance abuse, and unwillingness to participate in the study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depression symptoms. Timepoint: At baseline (before intervention) and the second and fourth weeks after intervention. Method of measurement: The Hamilton Rating Scale.

Secondary Outcome Measures

Name	Time	Method
Severity of the disease. Timepoint: At baseline (before intervention) and the second and fourth weeks after intervention. Method of measurement: Clinical Global Impression–Severity scale (CGI-S).;Illness Perception. Timepoint: At baseline (before intervention) and the second and fourth weeks after intervention. Method of measurement: the Brief Illness Perception Questionnaire (Brief IPQ).