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An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

Not Applicable
Recruiting
Conditions
Dry Eye
Interventions
Drug: Placebo
Registration Number
NCT07179055
Lead Sponsor
Vanda Pharmaceuticals
Brief Summary

The purpose of this study is to determine the safety and efficacy of VSJ-110 compared to placebo in the treatment of dry eye.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
160
Inclusion Criteria
  • Be at least 18 years of age of either gender and any race.
  • Provide written informed consent and sign the HIPAA form.
  • Be willing and able to follow all instructions and attend all study visits.
Exclusion Criteria
  • Use of any of the disallowed medications during the washout and study period.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
VSJ-110 SolutionVSJ-110-
Placebo SolutionPlacebo-
Primary Outcome Measures
NameTimeMethod
Corneal StainingMeasured over an 8-week treatment period

Corneal Staining will be assessed by the investigator on a scale of 0-4, with a higher number indicating a higher grade of staining.

Secondary Outcome Measures
NameTimeMethod
Schirmer's Tear TestMeasured over an 8-week treatment period

Schirmer tear test strips are used to measure ocular fluid.

Eye Dryness Score (EDS) of the Visual Analogue Scale (VAS)Measured over an 8-week treatment period

EDS is reported by the subject using a 100-point scale (0=no discomfort and 100=maximum discomfort).

Trial Locations

Locations (1)

Vanda Investigational Site

🇺🇸

Lynchburg, Virginia, United States

Vanda Investigational Site
🇺🇸Lynchburg, Virginia, United States
Vanda Pharmaceuticals
Contact
202-734-3400

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