The effect of two types of chewing gum containing CPP - ACP and xylitol on caries-causing bacteria in the mouth.
- Conditions
- Initial caries & salivary mutans streptoccus.Caries limited to enamel
- Registration Number
- IRCT2014063018296N1
- Lead Sponsor
- International branch of shahid beheshti university of medical sciences &health services dental s
- Brief Summary
Abstract Background:Dental caries is associated with oral pathogenes and Streptococcus mutans (S. mutans)is one of the primary cariogenic organisms. The aim of this clinical study was to evaluate the effect of sugar free chewing gum containing casein phosphopeptide-amorphous calcium phosphate(CPP-ACP) and Xylitol on salivary Streptococcus mutan. Materials and Methods: 60 dental students, who volunteered after signing an informed consent, were randomly allocated to receive one of the following interventions: (A) Chewing gum containing CPP-ACP, (B) Chewing gum containing Xylitol. Subjects within the experimental groups chewed gum for 20 minutes, three times a day after meals for 3 weeks. Pre- and post-intervention unstimulated saliva samples were quantified for Streptococcus mutans count. Results: A statistically significant reduction (p
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
1. No tooth decay or caries. 2. Lack of systemic antibiotics during the last 3 months. 3. Topical fluoride therapy during the 4-week period before baseline were not include. 4. No signs of any gingivitis or periodontal diseases. 5. Do not have habitual use of dairy xylitol or recaldent chewing gum. 6. Do not have smoking habit. 7.Have no history of systemic disease. Exclusion criterion: patients will to be excluded from the study.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Streptococcus mutans. Timepoint: Baseline salivary streptococcus mutans and after chewing gum salivary SM is measured. Method of measurement: Saliva is collected by sterile micro tubes.
- Secondary Outcome Measures
Name Time Method Side effects of CPP-ACP has been not reported but people who have allergies to milk not to use the gum. Timepoint: During of study. Method of measurement: If see any signs.