The effect of two typs of chewing gum containing casein phosphopeptide-amorphous calcium phosphate and xylitol on amounts of streptococcus mutans.
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
Abstract Background:Dental caries is associated with oral pathogenes and Streptococcus mutans (S. mutans)is one of the primary cariogenic organisms. The aim of this clinical study was to evaluate the effect of sugar free chewing gum containing casein phosphopeptide-amorphous calcium phosphate(CPP-ACP) and Xylitol on salivary Streptococcus mutan. Materials and Methods: 60 dental students, who volunteered after signing an informed consent, were randomly allocated to receive one of the following interventions: (A) Chewing gum containing CPP-ACP, (B) Chewing gum containing Xylitol. Subjects within the experimental groups chewed gum for 20 minutes, three times a day after meals for 3 weeks. Pre- and post-intervention unstimulated saliva samples were quantified for Streptococcus mutans count. Results: A statistically significant reduction (p
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 25 years（—）
- 性别
- All
入选标准
- •1. No tooth decay or caries. 2. Lack of systemic antibiotics during the last 3 months. 3. Topical fluoride therapy during the 4-week period before baseline were not include. 4. No signs of any gingivitis or periodontal diseases. 5. Do not have habitual use of dairy xylitol or recaldent chewing gum. 6. Do not have smoking habit. 7.Have no history of systemic disease. Exclusion criterion: patients will to be excluded from the study.
排除标准
- 未提供