Double Blind Placebo and Active (Caffeine) Controlled Study to Examine the Effects of 3 Doses of "WakeUp" Herbal Beverage Containing Green Tea (Instead of Ginkgo Biloba) on Vigilance and Function of Healthy Volunteers Following Lunch

This is a randomized, double-blind, controlled study with placebo and active control, to test the efficacy and safety of WakeUp on alertness and function in 30 healthy or chronically ill but stable adult volunteers.

Participants and recruitment Thirty volunteers will be recruited via advertisements (in the hospital and university environment). Initial assessment of inclusion and exclusion criteria will take place on the primary visit, and once participants have met the criteria for participation and sign an informed consent, they will enter the study and undergo randomization. It is permitted for participants to have any chronic disease (such as hypertension or diabetes) if they are stable and controlled. Participants will continue taking their own medications (as long as they are not stimulants or sedating, in which case the subject will be excluded).

Study procedure and schedule This is a single center, double-blind, placebo and active controlled clinical trial comprised of a single drink of WakeUp® beverage (in 3 doses) compared to caffeine (100mg) and placebo given to health volunteers. Participants will be randomized regarding the order of the various beverages.

The following visits and schedule will comprise the study:

1. Screening visit: In this visit study procedures will be expained, inclusionqexclusion criteria determined, informed consent signed).
2. Visit 1: Participants eats their regular lunce following which a first set of studies takes place (see below). Immediately thereafter the participant drinks the tested beverage (marked A, B, C, D, E or F, randomized order regarding which beverage of the 6 is drank at each specific study day, blinded to the participant and the staff). Thirty minutes after drinking a second set of studies will take place (exactly equal to the previous set of studies). A third set of studies (exactly the same as the previous two) will take place 2 hours following the drink.
3. Visits 2, 3, 4, and 5 are exactly like visit 1, just that the beverage is one of the others (randomized), such that each participants after completing 5 visits had all tested beverages: placebo, 100mg Caffeine, WakeUp® regular dose, WakeUp® double dose, WakeUp® triple dose.
4. Visit 7: A telephone call or a face-to-face visit (based on the preference of the participants) one week after the study to make sure there are no side effects and to close participation.