DRKS00010478
Recruiting
Not Applicable
Prospective, open, multicentre observational clinical study to inves- tigate safety and efficacy of cell-free Autologous Conditioned Serum (ACS) in patients with knee osteoarthritis with 3 years follow-up - OrthoR
ORTHOGEN AG0 sites1,000 target enrollmentNovember 14, 2016
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- M17.0
- Sponsor
- ORTHOGEN AG
- Enrollment
- 1000
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Confirmed Knee OA (Kellgren\-Lawrence Grades II–IV) diagnosis with imaging proceders (e.g. x\-ray, CT, MRI) not older than 6 month
- •2\) Knee pain for at least 4 weeks and pain intensity NRS \=5
- •3\) Treatment initiation with ACS
- •4\) Signed informed written Patient´s Informed Consent Form
Exclusion Criteria
- •1\) Previous knee operations in the last 6 months (Surgery and/or diagnostic arthroscopy)
- •2\) History of clinically significant trauma
- •3\) Intra\-articular injections in the last 3 months with steroids, hyaluronate compounds or PRP, ACS, ACP
- •4\) RA or autoimmune cause of arthritis, systemic bone or joint illnesses
- •5\) Active inflammation of predominant patella\-femoral disease
- •6\) BMI\>30
- •7\) Malignancy
- •8\) Infection
- •9\) Pregnancy
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
A multicenter, open, prospective observational study to confirm the clinical efficacy and safety after drug change in patients with degenerative arthritis (spondyloarthritis, knee arthritis) treated with anti-inflammatory analgesicsDiseases of the musculoskeletal system and connective tissueKCT0007770Yonsei University Health System, Severance Hospital800
Active, not recruiting
Phase 1
Pharmacokinetics of tacrolimus in the first days after heart and lung transplantatioHeart and lung transplantation, first days after transplantationMedDRA version: 19.0Level: LLTClassification code 10053349Term: Pharmacokinetic studySystem Organ Class: 100000004848Therapeutic area: Body processes [G] - Physical Phenomena [G01]EUCTR2012-001909-24-NLniversity Medical Center Utrecht30
Completed
Not Applicable
A prospective, open label, multi-centre, observational, post-market study evaluating Juvéderm® Volift with Lidocaine for the correction of moderate to severe nasolabial folds (NLF)gezichtverouderingdermal fillersfacial agingNL-OMON37130Allergan Pharmaceuticals Ireland23
Recruiting
Not Applicable
Prospective assessment of nProfiler® 1 predictive test on prognosis and chemotherapy response for resectable gastric cancerNeoplasmsKCT0005445ovomics688
Recruiting
Not Applicable
An observational registry study of ISAR SUMMIT coronary stent system in coronary artery diseased patients of Indian populatioHealth Condition 1: I251- Atherosclerotic heart disease of native coronary arteryCTRI/2022/07/044472Dr Praveen Chandra