Efficacy of Platelet Rich Plasma in treatment of knee osteoarthritis: A single group Pre & Post intervention QUASI Experimental study. - Nil

JLN Medical College0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月1日

试验速览

暂无简介。

•Patients aged 45-65 years with either side OA knees (ASA class I and II) of either gender
•History of pain in last month
•Those with imaging findings (X-ray) of degenerative changes of the joint without significant deformity (diagnosed by KL classification ( Grade 2 and 3)

•Patients with KL grading I ( doubtful disease) and grade 4 (Severe disease)
•Patient with history of diabetes mellitus
•On Immunosuppressive drugs
•Collagen vascular disorders
•Cancer or malignant disorders
•Active infection/ wound of knee
•Patients with autoimmune and platelet disorders
•Treatment with anticoagulant and antiplatelet medications within 10 days before injection
•Use of NSAIDs within 2 days before injection or unwilling to stop then post injection except paracetamol
•History of knee articular injection of corticosteroid during previous 3 months or use of systemic corticosteroids 2 weeks before PRP injection
•Patients with genu valgum/Varum greater than 20 degrees
•Human immunocompromised virus, Hepatitis B virus, Hepatitis C virus, venereal Disease Research Laboratory virus positive cases
•Knee surgery on affected side within last 12 months
•Systemic or inflammatory knee disease
•Presence of warm and tense joint effusion
•High chances of loss of follow-up
•History of trauma to affected knee

发起方

JLN Medical College