Role of Ultrasound Guided Transversus Abdominis Plane Block in Pain Control After Hepatectomy

Not Applicable

Not yet recruiting

• Conditions: Analgesia
• Interventions: Procedure: ultrasound guided subcostal TAP block; Procedure: ultrasound guided combined posterior and subcostal TAP block

• Registration Number: NCT06224179
• Lead Sponsor: Ain Shams University

Brief Summary

Inadequately managed acute pain following abdominal surgery originates from somatic pain signals in the abdominal wall and is linked to various unfavorable postoperative outcomes. These consequences encompass patient distress, respiratory complications, delirium, myocardial ischemia, extended hospital stays, an elevated risk of chronic pain, heightened analgesic consumption, delayed bowel function, and an increased need for rescue analgesics.

This study aims to assess the postoperative analgesic efficacy of ultrasound-guided Transversus Abdominis Plane (TAP) block using oblique subcostal and posterior approaches in hepatectomy.

Detailed Description

Pain control is vital to achieve enhanced recovery after abdominal surgeries . TAP block had been demonstrated to improve pain related outcomes after abdominal surgeries.

Postoperative pain management for patients undergoing hepatic resection is a challenge due to the risk of perioperative liver dysfunction.TAP block is a promising regional analgesic technique. This study aimed to evaluate the effect of US-guided subcostal approach versus combination of both subcostal and posterior approaches of TAP block

The patients will be randomly divided into two groups :

group A will recieve oblique subcostal TAP block and group B will recieve both subcostal and posterior TAP block .

Study Timeline

• Status Verified: 2024-01
• Study First Submitted: 2024-01-17
• Study First Submitted QC: 2024-01-17
• Study First Posted: 2024-01-25
• Last Update Submitted: 2024-01-29
• Last Update Posted: 2024-01-30
• Study Start: 2024-02-01
• Primary Completion: 2024-05-01
• Study Completion: 2024-06-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• ASA I and II patients. aged 18 to 50 years. 70 to 80 kg.

Exclusion Criteria

• patients under 18 years of age.

  • History of Allergic reactions to study drugs.
  • Opioid or analgesic abuse, and chronic treatment with opioids, or non-steroidal anti-inflammatory drugs.
  • History of bleeding tendency or coagulopathy .

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group A	ultrasound guided subcostal TAP block	Group A received ultrasound guided subcostal TAP block with 30 ml of local anesthetics and additives
Group B	ultrasound guided combined posterior and subcostal TAP block	Group B received ultrasound guided both subcostal and posterior TAP block with 30 ml of local anesthetics and additives at each side

Primary Outcome Measures

Name	Time	Method
postoperative analgesia (VAS) during the 1st 24 hours in ICU	24 hours	Pain will be assessed on admission and at 2, 4, 8, 12 and 24 hours at rest and with passive flexion of hip and knee joint using visual analogue scale (VAS) ranging from 0 for no pain to 10 for worst pain.