Feasibility and safety of Umbilical cord blood as a potential source for blood transfusion in neonates - Prospective cohort study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- umbilical cord blood
研究概览
简要总结
Hypothesis of this study-It is feasible to separate and store packed red blood cell from umbilical cord blood and use it as a source for neonatal blood transfusion when required.primary purpose of this study to estimate the amount of umbilical cord blood that can be collected per neonate following delayed cord clamping across different gestational ages,birth weight,mode of delivery and methods of collection.safety of the umbilical cord blood in terms of hematological,microbiological and biochemical quality on storage.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0.00 Day(s) 至 1.00 Day(s)（—）
- 性别
- All
入选标准
- •Mothers who consent for collection and storage of their Umbilical cord blood at the time of delivery.
排除标准
- •Mothers diagnosed with HIV/HBV/HCV/Malaria/Syphilis infection
- •Mothers who opt for stem cell storage from Umbilical cord blood.
结局指标
主要结局
umbilical cord blood
时间窗: 0, 7, 14, 21, 30 days
• Potassium (0, 7,14,21,30 days)
时间窗: 0, 7, 14, 21, 30 days
• Free Haemoglobin (0, 14, 28days)
时间窗: 0, 7, 14, 21, 30 days
• Cord blood culture (0,14 days)
时间窗: 0, 7, 14, 21, 30 days
1. Quantity of umbilical cord blood (ml) that can be collected per neonate across different gestational age, birth weight, mode of delivery and collection method 2. Change in Parameters of collected and stored
时间窗: 0, 7, 14, 21, 30 days
• Haematocrit (0, 7,14,21,30 days)
时间窗: 0, 7, 14, 21, 30 days
• pH (0, 7, 14, 21, 30 days)
时间窗: 0, 7, 14, 21, 30 days
次要结局
- Quantity of packed RBC(ml) that can be(separated from the umbilical cord blood after)