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Clinical Trials/NCT02692664
NCT02692664
Completed
Not Applicable

Prospective Multicenter Study for the Endovascular Treatment of Iliac Aneurysm With the Branched E-liac Stent Graft

JOTEC GmbH2 sites in 1 country71 target enrollmentMay 1, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Iliac Aneurysm
Sponsor
JOTEC GmbH
Enrollment
71
Locations
2
Primary Endpoint
Clinical success
Status
Completed
Last Updated
2 months ago

Overview

Brief Summary

In this study, patients will be observed who receive an E-liac Stent Graft for treatment of isolated iliac aneurysms or an E-liac Stent Graft in combination with one of the following AAA stent grafts: E-tegra Stent Graft, Endurant AAA Stent Graft, Zenith AAA Endovascular Graft, Gore Excluder AAA Endoprosthesis for treatment of aorto-iliac aneurysms.

Objectives of this post-market registry are:

Primary: To prevent the risk of rupture and death by the treatment of common iliac aneurysm with an iliac branched stent graft (E-liac, JOTEC) Secondary: Evaluation of safety and feasibility of the E-liac Stent Graft System used in endovascular treatment of uni- or bilateral aorto-iliac or iliac aneurysm.

Registry
clinicaltrials.gov
Start Date
May 1, 2016
End Date
July 5, 2024
Last Updated
2 months ago
Study Type
Observational
Sex
All

Investigators

Sponsor
JOTEC GmbH
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Unilateral or bilateral aorto-iliac or iliac aneurysm
  • Suitable for endovascular repair
  • Patient must be compliant with life- long follow-up investigations
  • \>18 years old
  • lliac/femoral access vessel morphology compatible with the implantation procedure and the 18Fr (6mm OD) delivery system
  • Non-aneurysmal common iliac artery landing area in case of iliac artery aneurysm ≥ 20mm
  • Diameter of the common iliac artery in the proximal landing area: 12mm to 17mm
  • Non-aneurysmal external iliac artery segment distal to the aneurysm ≥15mm
  • Diameter of the external iliac artery in the distal landing area: 8mm to 13mm
  • Non-aneurysmal internal iliac artery segment distal to the aneurysm ≥15mm

Exclusion Criteria

  • Patients who do not meet the instructions for use
  • Patients with one of the contraindications as indicated in the instructions for use
  • Patients with a stenotic internal iliac ostium of \< 4mm in Diameter
  • Patients with severe internal iliac atherosclerosis
  • Patients that do not have a suitable landing area in the main stem of the IIA (maximum diameter in landing area \<12mm)
  • Patients with pseudoaneurysms
  • Patients with symptomatic and ruptured iliac aneurysms
  • Patients pretreated with a AAA stent graft or a bifurcated vascular graft
  • Patient with thrombocytopenia
  • Patient with an estimated glomerular filtration rate \< 30 ml/min/1,73m2 immediately before the Intervention

Outcomes

Primary Outcomes

Clinical success

Time Frame: 30 days follow-up

Clinical success related to the E-liac Stent Graft combines the following criteria (adapted from Chaikof 2002): * Clinical success should be reported on an intent-to-treat Basis * requires successful deployment of the E-liac Stent Graft at the intended location without * Death as a result of iliac aneurysm-related treatment * Type I or III endoleak * E-liac Stent Graft infection * E-liac Stent Graft thrombosis (including internal iliac artery thrombosis) * Aneurysm growth \>3mm in maximum diameter for common iliac aneurysm and \>5mm in maximum diameter for aortic aneurysm at 12, 24, and 36 months follow-up * Common iliac aneurysm rupture * Conversion to open repair * Failure of E-liac Stent Graft integrity

Study Sites (2)

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