Finding best practice: use of s-ketamine peropertively and in patient controlled analgesia in the treatment of pain after major abdominal surgery
Recruiting
- Conditions
- Analgesia in abdominal surgery1006291510043413
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
The patient has provided written informed consent prior to admission to the study
The patient is between 18 and 70 years of age
Exclusion Criteria
The patient has a history of uncontrolled chronic disease which would contra-indicate study participation.
The patient has severe systemic disease that limits activity and is a constant threat to life (ASA IV).
The patient has a history of chronic substance abuse within the last 3 months.
The patient has a history of psychiatric disorders.
The patient has a history of hypersensitivity to one of the study drugs.
The patient has a history of severe chronic respiratory disorders.
The patient is either breastfeeding or pregnant.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>1. The total morphine use over 72 hours.<br /><br>2. The occurence of side effects.<br /><br>3. The VAS scores per study group.</p><br>
- Secondary Outcome Measures
Name Time Method <p>1. Evaluation of the levels of the amino-acids (glutamate, glycine, tryptofane,<br /><br>arginine e.g) and the effect of analgesia on them.</p><br>