DRKS00013497已完成不适用
Study on the incidence of genetic polymorphism in patients with major depression who are treated unsatisfactory with antidepressants - GENADET
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 252
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one(—)
- 性别
- All
入选标准
- •Outpatients with a diagnosis of major depression
- •First drug treatment with one of the following active substances since max. two weeks:
- •-Citalopram
- •-Escitalopram
- •-Amitriptyline
- •-Venlafaxine
- •Age =18 years
- •Capacity to consent
排除标准
- •Comedication with influence on the activity of the enzymes CYP2C19 and CYP2D6
- •Intake of St. John's wort preparations
- •Consumption of grapefruit and / or products
- •Consumption of tryptophan-containing dietary supplements
- •Change of medication within the last 3 months
- •Hepatic insufficiency (from Child-Pugh-stage A)
- •Renal insufficiency stage 3 (glomerular filtration rate <60 ml / min / 1.73 m²)
- •Addiction
- •Schizophrenia
- •Bipolar affective disorder
- •Pregnancy or breastfeeding
- •Participation in an interventional study
研究者
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