The Early Prediction of Sepsis in ICU

• Conditions: Prediction of Sepsis in Critical Patients
• Interventions: Other: no intervention

• Registration Number: NCT05088850
• Lead Sponsor: Ruijin Hospital

Brief Summary

Sepsis is a vital issue in critical care medicine, and early detection and intervention are key to survival. We aimed to establish an early warning system for sepsis based on a data integration platform that can be implemented in the ICU.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-30
• Status Verified: 2021-10
• Study First Submitted: 2021-10-18
• Study First Submitted QC: 2021-10-19
• Last Update Submitted: 2021-10-19
• Study First Posted: 2021-10-22
• Last Update Posted: 2021-10-22
• Primary Completion: 2022-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

Patients who met all of the following criteria were included in the case group:

1. At least 14 years old.
2. Sepsis onset at least 5 hours after ICU admission.
3. Sepsis onset is the first instance since admission to the hospital.

Exclusion Criteria

Patients meeting all of the following criteria were included in the control group:

1. At least 14 years old.
2. Patients staying in ICU for at least 5 hours and have not had sepsis in this time.
3. Patients without ICD-9 codes for sepsis (785·52, 995·91, 995·92).
4. SOFA score change is not more than 1 point in an arbitrary continuous 72 hours in the ICU stay.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
non-sepsis	no intervention	-
sepsis	no intervention	-

Primary Outcome Measures

Name	Time	Method
confidence index of sepsis occurrence	sepsis occurrence in five hours

Trial Locations

Locations (1)

ICU, Ruijin Hospital; 🇨🇳 Shanghai, Shanghai, China