Evaluation of optical coherence (OCT), imaging to examine the structure and form of coronary plaques following a heart attack.

Not Applicable

• Conditions: Coronary Artery Disease; Non-ST elevation Myocardial Infarction; Thrombolysed STEMI; High risk Acute coronary syndrome; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12615001234505
• Lead Sponsor: niversity of Western Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-11
• Last Update Posted: 21 September 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Patients presenting to hospital with:
NSTEMI proceeding to in-patient angiography
STEMI proceeding to non-emergency in-patient angiography (late presentation or reperfused without PCI)
All major epicardial coronary arteries suitable for for OCT prior to stenting (intervention).
The time point is during that hospital admission for the MI event. Simply in-patient angiography.

Exclusion Criteria

eGFR <40ml/min with diabetes mellitus
unlikely to survive for at least 3 years due to a co-morbidity
coronary anatomy unsuitable for OCT
pregnancy
prior coronary Bypass Graft
STEMI treated with PCI.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major Adverse Cardiac Events (Cardiovascular disease, death, MI, revascularisation). Via telephone follow-up and hospital records.[5 years post OCT.]

Secondary Outcome Measures

Name	Time	Method
Accuracy of OCT as a predictor of future MACE risk, assessed with OCT data and review of hospital records for MACE outcomes.[5 years post OCT]